Available Technologies

Office of Research & Technology Transfer

Available Technologies

Researchers at Colorado School of Mines are on the forefront of innovation. Our faculty and staff are dedicated to providing creative solutions to a wide range of scientific and engineering challenges. For more information, contact Will Vaughan, Director of Technology Transfer (wvaughan@mines.edu).

TitleInventorsDepartmentCategorySummaryPriority DateSerial/Patent Number
Fiber-Focused Diode-Bar Optical Trapping for Microfluidic Flow ManipulationJeff Squier, David Marr, Robert Applegate, Tor VestadChemical Engineering
Physics
Photovoltaics and Spectroscopy A simple, inexpensive fiber-based approach that allows for easy implementation of diode-bars for optical particle separations within flowing microfluidic systems.2007-09-269878326
Lanthanide Nanoparticle Conjugates and Uses ThereofStephen Boyes, Misty Rowe;Douglas Thamm, Susan KraftChemistry and GeochemistryBiosciencesGold/lanthanide nanoparticles with and without polymers grafted to, or polymerized form, the surface of lanthanide (e.g., gadolinium) nanoparticles. The polymers have functional groups that may be derivatized to include imaging, therapeutic and/or targeting agents at their surface.2008-08-228916135
Optical-Based Cell DeformabilityJeff Squier; David Marr; Robert Applegate; Tor Vestad; Justin ChichesterPhysicsPhotovoltaics and Spectroscopy A method to measure cell deformability in a dynamic, flowing system, using an integration of novel laser configurations within a microfluidic system. This optical stretching is able to distinguish between normal, cancerous and metastatic mouse fibroblast and human breast epithelial cells.2007-07-038119976
Microfluidic flow assay for measuring hemostatic phenotypesKeith Neeves, Ryan HansenChemical EngineeringBiosciencesThis microfluidic flow assay is a method for measuring an individual’s propensity to form a blood clot. The assay consists of a micropatterned surface that induces clot formation and an array of microfluidic channels through which blood flows. 2010-03-128486349
Spatially chirped pulses for femtosecond laser ablation through transparent materialsJeff Squier, Dawn Vitek, Charles Durfee, Dan Adams, David KleinfledPhysicsPhotovoltaics and Spectroscopy A method for micromachining high aspect ratio features in thick media using temporal focusing of spatially chirped femtosecond laser pulses2010-09-218669488
9545689
Wave-Equation Migration Velocity Analysis Using Image WarpingPaul Sava, Francesco Perrone, Clara Andreoletti, Nicola BienatiGeophysicsSensorsA method to construct velocity models for imaging the interior of the Earth using wavefield-based methodology and the discrepancies between images constructed using redundant seismic experiments. 2011-07-129702997
Polylactide-Graft-Lignin CopolymersJohn Dorgan, Mike Eyser,Clay PerbixChemical EngineeringMaterials and PolymersMethods to produce renewable polyactide-graft-lignin blends and copolymers2012-03-268993705
Microfluidic Flow Assay and Methods of UseKeith Neeves, Abimbola OnasogaChemical EngineeringBiosciencesA plasma-based flow assay for measuring thrombin and fibrin generation, the two end products of the coagulation cascade. It integrates the coagulation cascade into a fluidic architecture, which allows for measurement of these coagulation products under the hemodynamic conditions found in the body.2012-06-279709579
Solubilizing Imide Precursors for Poorly Soluble PolymersDan KnaussChemical EngineeringMaterials and PolymersA method for making polyimides and other rigid conjugated polymers via soluble amide-ester precursors. This method has high thermal stability compatible with high temperature processing and the ability to easily manipulate insoluble materials through a soluble precursor2013-01-309355787
Biodegradable Polymers for Delivery of Therapeutic AgentsMelissa KrebsChemical EngineeringBiosciencesAn injectable antibody-laden biodegradable hydrogel that allows the antibodies to remain localized and be steadily released in a controlled manner over a sustained period of time. The delivery system should enhance efficacy of the therapeutic agent by increasing the local concentrations and prolonging the exposure of the treatment site.2014-06-249657094
Alumina-Rich Glasses and Methods for Making the SameIvan Cornejo, Ivar ReimanisMetallurgical and Materials EngineeringMaterials and PolymersA low-temperature method for making aluminum rich glasses that have high chemical durability and mechanical properties that are close to sapphire single crystals2013-05-219359244
Pressure Oxidation of Enargite Concentrates Containing Gold and silverCorby Anderson , Kim ConnerMetallurgical and Materials EngineeringMining and MineralsA method to separate copper and arsenic at moderate temperatures and pressures2013-11-0111149328
De-Zincing Zinc-Coated MetalsCorby Anderson, Joe Grogan, Gerald MartinsMetallurgical and Materials EngineeringMining and MineralsThis invention uses an electrochemical-based technique to selectively remove the zinc coating from the substrate metal. Novel hydrometallurgical-methods are subsequently employed for reagent recovery. 2014-02-2510087502
Purification of Yttrium Using Iminodiacetic Acid ResinCorby Anderson, Ben KronholmMetallurgical and Materials EngineeringMining and MineralsA method to selectively separate yttrium from heavy rare earth mixtures2013-12-0510696562
3D Gaze Control of Robot for Navigation and Object ManipulationXiaoli Zhang, Songpo LiMechanical EngineeringComputer Science and Quantum ComputingA three-dimensional (3D) gaze-based robot control system to guide robots for navigation and object manipulation. In this method, individuals can use their eyes to operate assistive robots for identifying, approaching, and manipulating target objects. 2015-09-2110157313
10755096
Autonomous Robotic Laparoscope based on Eye TrackingXiaoli Zhang, Songpo LiMechanical EngineeringComputer Science and Quantum ComputingThis system allows the robot to unobtrusively monitoring the surgeon’s gaze movements to track their viewing attention and to automatically adjust the field of view correspondingly.2015-09-2110682038
Interferometric Characterization for Divergence and Spatial ChirpCharles Durfee, Amanda MeierPhysicsPhotovoltaics and Spectroscopy A spectral interferomic method to optimize intensity-localization in spatio-temporally focused ultrafast beams2014-10-179964449
Integrated Single Grating compressor for Variable Pulse Front Tilt in Simultaneously Spatially and Templorarily Focused SystemsJeff Squier, Erica BlockPhysicsPhotovoltaics and Spectroscopy A multipass chirped pulse amplification system that is outfitted with a single grating, simultaneous spatially and temporal focusing compressor platform. This novel design has the ability to easily vary the beam aspect ratio of a spatially and temporal focusing beam, and thus the degree of pulse front tilt at focus, while maintaining a net zero-dispersion system. 2014-12-1210040146
Triple Conducting Cathode for Intermediate Temperature Protonic Ceramic Electrochemical DevicesJianhua Tong, Ryan O'Hayre, Meng Shang, Chuaneheng DuanMetallurgical and Materials EngineeringRenewable EnergyA novel perovskite-type multicomponent compound that displays high electrochemical performance at intermediate temperatures 2016-01-0810014529
10059584
Metal Oxide Laser Ionization-Mass SpectrometryKent Voorhees, Casey McAlpin, Ryan RichardsChemistry and GeochemistryBiosciencesA method to rapidly identify bacteria and fatty acid using MALDI mass spectrometry2012-03-1910079139
Ammonia Synthesis at Moderate conditions Using Hydrogen Permeable Membrane ReactorsDoug Way, Sean-Thomas Lundin, Colin WoldenChemical EngineeringRenewable EnergyThe synthesis of ammonia at moderate temperatures and pressures and potential on-site, scalable production2015-03-3110159969
Magnetic Field Driven Colloidal Microbots Employing Wall Based PropulsionTongue Tasci, Keith Neeves, David MarrChemical EngineeringBiosciencesA method to assemble, target, and disassemble microbots in the vasculature that can replace and improve upon current invasive procedures. This novel approach uses a combination of oscillating magnetic fields to create colloidal assemblies that roll along available surfaces. As a result, this method can be used to generate and control microbots that can translate throughout the body 10-100 times faster than competing procedures. 2015-03-1310722250
Controlled And Tunable Precipitation Of Biomietic Apatites Via In Situ Mineralization Of An Organic Polymeric MatrixJacqueline Harding, Melissa KrebsChemical EngineeringBiosciencesThe precipitation of biological apatites within a polymeric support substrate which closely resembles natural bone tissue, allows for tuning of the chemical composition and uses a controlled deposition of the mineral phase2015-06-0110806827
10926000
Functionalized Poly(diallylpiperidinium) and its copolymers for use in ion conducting applicationsDaniel M. Knauss, Derek J. StrasserChemistry & GeochemistryMaterials and PolymersA method to synthesize water insoluble, highly alkaline stable membranes for conductivity fuel cells, electrolysis devices, and batteries2017-08-2211745148
Mechanical Stiffening of Wurtzite Piezoelectrics by Boron Nitride DopingVladan Stevanovic, Sukriti Manna, Geoff Brennecka, Cristian CiobanuMetallurgical and Materials EngineeringMaterials and PolymersA method which maintains or increases the stiffness of piezoelectric material through additional alloying with boron nitride (BN), while retaining sufficient piezoelectric enhancements from the alloying with the more common piezo-enhancing nitride (CrN, ScN or YN).2017-10-1311765977
Boron Compounds for Admixture to ScintillatorsCory Pecinovsky, Pascale Meysing, Adam Mahl, John Dorgan, Uwe Greife, Tyler RemedesChemical EngineeringSensorsA method of synthesis and characterization of a novel 10B enriched aromatic molecule that can be incorporated into common poly(vinyltoluene) (PVT) based plastic scintillators to achieve enhanced thermal neutron detection. 2014-08-059796921
10698121
New Method of Functionalizing Fluoropolymers with Acidic Side Chains Exhibiting Improved PropertiesAndrew M. Herring, Mei-Chen Kuo, Andrew R. MotzChemical EngineeringMaterials and PolymersA fluoropolymer reaction that uses metal hydrides which: 1) reduces excess dehydrofluorination; 2) allows for controllable cross-linking of double bonds; 3) runs at a lower temperature; and 4) can be used to incorporate heteropoly acid2017-08-2510961336
Superelastic Ferroelastic CeramicsTaylor Wilkinson, Matt Musselman, Corinne PackardMetallurgical and Materials EngineeringMaterials and PolymersA method to synthesize superelastic ferroelastic ceramics that absorb and release vast quantities of mechanical energy and can do so across very wide temperature ranges. The resulting material is also oxidation and corrosion resistant for use in extreme environments2017-11-3011027976
High Efficiency Solid Oxide Fuel CellRobert Braun, Todd Brandhauer, Daniel Olsen, Bret WindomMechanical EngineeringRenewable EnergyA hybrid stationary power generator fueled from natural gas and based on solid oxide fuel cells and high efficiency, internal combustion engine technologies is conceived to generate electric power at 100-kW scale with an efficiency of 71% and a capital cost of <900 $/kW. 2017-12-2211145880
System and Method of Extracting Water from Regolith on the MoonGeorge F. Sowers Jr., Christopher Brian DreyerMechanical EngineeringEnviroment and WaterA method to extract water ice from the regolith in Permanently Shadowed Regions near the poles of the Moon. These techniques make use of direct heating of the regolith and avoid energy intensive and costly excavation.2018-03-0211905833
Aberration Correction for Atom Probe TomographyBrian P GormanMetallurgical and Materials EngineeringPhotovoltaics and Spectroscopy This invention develops several new techniques to reach the goal of atomic scale tomography (AST), including in-situ electron microscopy imaging of atom probe specimens, wide field of view ion detector integration for AST, and new 3-D data reconstruction algorithms that overcome many of the current limitations of atom probe data analysis.2018-04-1310755891
Software Security System 2018Matthew Sanders, Chuan YueComputer ScienceComputer Science and Quantum ComputingA method for generating least privilege policies from access logs using a supervised learning classification algorithm or unsupervised learning clustering algorithm.2018-10-1611470122
Identification of Defects in Metal During Continuous CastingMatthew Zappulla, Brian ThomasMechanical EngineeringMaterials and PolymersThis invention uses methodologies for post processing, as well as the selection of some visualization parameters, for a variety of variables and models relevant to understanding and quantifying the complex phenomena in steel continuous casting. A methodology is described for the processing of high-density data from temperature sensors to better visualize potential quality issues on the surface of a continuously cast slab.2019-01-2811360039
Compounds, Methods, And Systems For Benefication Of Rare Earth Elements By Flotation And Gravity ConcentrationAlex Norgren, Nathanael Williams, Dylan Everly, Corby AndersonMining EngineeringMining and MineralsA new method to recover rare earth minerals from ores using centrifugal concentrators to beneficiate Ultra-Fine (UF) bastnaesite and calcite bearing flotation concentrates. This method recovers rare earth elements from ores in higher percentages than currently possible and can be easily integrated into current ore separation methods2020-08-0217/392,102
Fuel Cell with Planar Stacking LayersBob Kee, Huayang ZhuMechanical EngineeringRenewable EnergyThis invention describes a dual-spiral channel architecture offering substantial improvements compared to the current state of the art for technologies that are based on electrically polarized, ion-conducting, membranes, such as fuel cells, electrolyzers, and membrane reactors 2019-09-2311996565
Methods Of Making YSZ Supported Catalyst, And Methods Of Using The SameDouglas Way, Colin Wolden, Zhenyu ZhangChemical EngineeringRenewable EnergyThis invention describes a catalyst used for continuously synthesizing ammonia using a gas containing hydrogen and nitrogen as a raw material and a transition metal such as ruthenium promoted by alkali metals such as Cs, K, or Ba provides catalytic activity, supported by a yittria stabilized zirconia (YSZ) framework .2019-08-1411925921
Quantum Machine Learning System Using RFQA Quantum OptimizationEliot KapitComputer ScienceComputer Science and Quantum ComputingThis method encompasses methods to improve RFQA including new lossy elements for quantum accelerated cooling, using of RFQA to accelerate thermalization in quantum machine learning, and adaptations of this scheme to digital quantum computers. The method uses ancilla qubits and frequent state resets as a cooling mechanism to accelerate performance and mitigate errors.2019-09-2017/027,146
Device Fingerprint-based Spoof-proof Secure Phone-as-a-KeyDejun YangComputer ScienceComputer Science and Quantum ComputingA spoof-proof secure smart key system which leverages the device fingerprint resulted from manufacturing imperfection. Like human fingerprints, a device fingerprint can be used to uniquely identify a device. Upon receiving the radio signal, the car will extract the fingerprint from the signal and compare it with the stored key fob fingerprint for authentication. This is a software-based solution and does not require extra hardware or devices and does not require modifying the current communication protocol between the key fob and the car.2020-10-1411887418
Bifunctional Catalysts and Systems and Methods for Oxidative Dehydrogenation of Alkanes to Olefins and High-Valued ProductsCanan Karakaya, Bob Kee, Olaf DeutschmannMechanical EngineeringRenewable EnergyThis invention discloses catalysts and processes that use CO2 as a soft oxidizing agent to selectively convert low-value small alkanes (e.g., ethane, propane) to high-value small olefins (e.g., ethylene, propylene). 2020-03-2011724247
Nanosuspensions of Cannabidiol for Developing Water-Dispersible FormulationsAnuj ChauhanChemical and Biological EngineeringBiosciencesA novel composition and a method of water-soluble CBD using melt emulsification and solvent evaporation. 2020-05-2211975098
Method of Making Anhydrous Metal ChalcogenidesWilliam Smith, Colin WoldenChemical and Biological EngineeringMaterials and PolymersAn improved method of making anhydrous metal sulfides (MSx) from a Lithium catalyst. Such MSx compounds can be used in making batteries, catalysts, semiconductors and advanced lubricants.2020-02-2117/180,479
Protonic Ceramic Fuel Cell SystemRobert J. Braun, Alexis Dubois, Kyle J. FergusonMechanical EngineeringRenewable EnergyThis invention describes an innovative system configuration for power generation applications using novel protonic ceramic fuel cells (PCFC) electrochemical technology at the heart of the system and explores the performance characteristics of different, high efficiency PCFC system configurations.2023-06-0618/329,930
Advanced Systems and Methods for Leaching Rare Earths From Ore FieldGerald Colligan, Corby AndersonMining EngineeringMining and MineralsMining of rare earth elements such as Cerium, Lanthanum and Neodymium in the United States requires processing to recover the relatively small amounts from much larger amounts of samples. This new method is a single stage process that has a recovery rate (95%) far in excess of the current methods (60%) using a lesser amount of caustic chemicals2021-01-1517/575,357
Error-Divisible Quantum GatesEliot Kapit, David SchusterPhysicsComputer Science and Quantum ComputingA simple method by which additional signals are added into parametrically driven couplers in quantum computing systems to instantaneously cancel unwanted terms, leading to error-divisible quantum gates. 2020-12-3117/564,802
Tunable Capacitor For Superconducting
Qubits Using an InAs/InGaAs Heterostructure
Eliot Kapit, Nicholas Materise, Javad ShabaniPhysicsComputer Science and Quantum ComputingA gate-tunable coupler realized with a two-dimensional electron gas in an InAs/InGaAs heterostructure. The numerical simulations yield an on/off ratio of over two orders of magnitude. The proposed system also gives an estimate of the dielectric-limited loss from the inclusion of the coupler in a two-qubit system.2020-12-3117/564,789
Single Shot Spatial Frequency Modulation Imaging (SPIFI)John Czerski, Daniel Adams, Jeff SquierPhysicsPhotovoltaics and Spectroscopy This invention combinines super resolution optical measurement with precision laser machining (Femtosecond Laser Machining), which dramatically improves 3D printing of metal parts. This Spatial Frequency Modulation Imaging (SPFI) is a new super-resolution optical measurement technique that is compatible with laser-based advanced manufacturing.2021-07-2117/868,562
Efficient Geophysical Data Acquisition Method Using Sparse Irregular Samples Based on Ergodic Sampling TheoryMengli Zhang, Yaoguo LiGeophysicsComputer Science and Quantum ComputingA sampling theory and practical approach which uses ergodic sampling, requiring only a fraction of number of samples currently used to capture the same information. This sampling theory uses four efficient acquisition design criteria for practical application. Using these criteria, receiver-deployment patterns are generated which use a fraction (10%-50%) of stations traditionally required 2021-07-3017/877,304
Magnetite Ore Pelletizing Compositions, Devices, Systems, and Methods
Using Automotive Paint Sludge as a Binder
Corby Anderson, Victoria VaccarezzaMining EngineeringMining and MineralsA recycling application that employs the use of the automotive paint sludge material. The paint sludge is used as a binder for iron ore pellets, typically used for iron- and steelmaking.2021-11-0318/052,487
Airborne Delivery of MicrorobotsDavid Marr, Keith NeevesChemical and Biological EngineeringBiosciencesThis invention describes a method by which individual building blocks of microbots (µbots) are aerosolized and subsequently assembled in situ and are capable of translation and mechanical work deep within lung mimics. With this strategy, a variety of pulmonary diseases previously difficult to treat may now be susceptible to µbot-based therapies. 2021-11-0917/983,933
Functionalized aromatic phosphonic acids for applicationAlan Sellinger
Jinsong Huang (UNC)
Anastasia Kuvayskaya
Chengbin Fei (UNC)
PhysicsSensorsSolar cell technology, in which the synthesis, characterization, and purification of functionalized aromatic phosphonic acids (FAPA) using absorbing perovskite layers allows for changing electrochemical properties such as varying dipoles or the difference between opposing charges of molecules. This expands access of phosphonic acids that can be tuned for absorption into targeted sites of active material layers for hole extraction, which leads to a higher power conversion efficiency in solar cells2024-04-0363/574,079
Immobilized Hydrolytic DehalogenasesRick Holz
Karla Diviesti
ChemistrySensorsThis invention describes degrading hazardous organic compounds by cutting the carbon-chlorine bond in aromatic compounds and disabling two enzymes - TrzN and Chd. The disabling of the two enzymes serves to restrict activity to within the biomaterials while maintaining the ability to digest two main compounds of interest: chlorothalonil and atrazine. 2022-12-1618/544,148
Hyperspectral Data Interpretation Using Co-Registered Datasets and Artificial
Intelligence
Katharina Pfaff
Thomas Monecke
Amit Rotem
Luis Tenorio
Alexander Vidal
GeologyMining and MineralsMachine learning and artificial intelligence (AI) were used on different rock formations to gather hyperspectral infrared data such as light absorption data, texture, and abundance levels of minerals. The raw data produced from field assessments and scaled-up versions of datasets obtained from scanning electron microscopy (SEM) or X-ray fluorescence (XRF) were utilized to examine subsamples and can be used for examining drill core samples or waste rock/tailings. 2023-02-1518/441,842
Rapid electrochemical mapping of energy conversion devicesRyan O'Hayre
Jake Huang
Metallurgical and Materials EngineeringRenewable EnergyA methodology that synthesizes a detailed electrochemical map containing significant properties such as temperature, power performance, and corrosion potential for batteries and fuel cells. Probability-based data analysis is used to reveal hidden data-based relationships when examining electrochemical maps in certain datasets, which can improve quality control and innovative energy technologies.2023-02-2418/584,766
Superconducting Logical Qubit ArchitectureEliot KapitPhysicsComputer Science and Quantum ComputingA galvanically shunted tunable coupler for 3D microwave cavities. Using a SQUID in galvanic contact with the walls of a buffer cavity, we achieve high on/off coupling ratios and large SWAP rates between neighboring 3D cavities. This design significantly increases the coupling rate between neighboring cavities compared to existing fixed frequency aperture couplers and dipole-coupled flux-tunable transmon implementations. This design has the potential to overcome the 3D transmon coherence limit set by high electric field participation of the substrate, supporting further development of 3D cavity-based qubit and qudit systems.2022-07-0518/347,263
Photobioreactor Methods and Systems for Accurate Environmental Maintenance of
Biological Cultures
Devin Karns
Ed Dempsey
Chemical and Biological EngineeringBiosciences, SensorsAn automated photoreactor system to simulate outdoor pond growth, which consists of an engine cooled with liquid to promote high efficiency in photoreactions with controls for temperature, mass flow, and types of liquids. Using measurable parameters such as light exposure, temperature, and pH, the photoreactor monitors culture growth by electronic sensors to simulate outdoor pond conditions and volumetric tools such as weigh modules to maintain media layers and salinity levels.2023-06-0863/506,996
Hydrogen Permeable, Intermetallic Diffusion
Barriers Used in BCC Metal Membranes
Colin Wolden
Adam Job
Douglas Way
Chemical and Biological EngineeringRenewable EnergyA method consisting of a catalyst containing platinum group metals and body-centered cubic unit cells containing group IV metals are attached to a nitrogen atom, creating a diffusion barrier to promote a thin, permeable membrane layer that processes H2-metal complexes at high temperatures. Long-term thermodynamic stability and increased efficiency were demonstrated due to 100 percent selectivity and permeability with respect to hydrogen gases.2023-06-1263/472,530
Optical Concentrate Monitoring Algorithm for Membrane Scaling MitigationJohan Vanneste
Alexander Schwiebert
John Arthur Bush
Civil and Enviromental EngineeringSensorsA method monitoring membrane-based desalination of water, using parameters such as temperature, pH, and flow regime. Analysis of the concentrate stream, liquid feed and product streams uses any turbidity as an indication of crystallization occurring. Once detected, operators can then mechanically remove the scaling and tune the system to optimal conditions and prevent further scaling.2023-03-0718/180,045
Copper- and Cobalt-containing Ore Processing Methods and SystemsCorby Anderson
Emma Bishop
Mason Brevig
Luis Aguayo Torrez
Erik Spiller
Mining EngineeringMining and MineralsA method of separating copper and cobalt concentrates by floating at high pH with starvation dosage of collector.  Optimized recovery to copper concentrate at 20.9% with only 3.98% cobalt. 2024-02-2063/555,714
Characterizing and monitoring subsurface
stimulated serpentinization for geologic hydrogen
Mengli Zhang
Yaoguo Li
GeophysicsComputer Science and Quantum ComputingA method to monitor geologic hydrogen and that tracks geophysical properties and data from the serpentinization process is utilized in the field to map out locations and process activity. This data can be applied to direct decision making in the field such as water and catalyst injection locations in subsurface formations at the Earth’s crust2023-12-2063/613054
Methods for the Fast Approximation and Solving of Hard Optimization Problems
on a Quantum Computer
Eliot KapitComputer ScienceComputer Science and Quantum ComputingTwo algorithms that optimize cost functions to simplify and solve complex problems. The first algorithm is spectral folding, in which the energy cost function is picked apart and then the data set is scattered so that approximate solutions are returned for a wide range of problems in a ground state band for fields like molecular biology. The second algorithm is IST-SAT, in which previous sample data is correlated to tuning parameters and then converges into ground state data when initialized properly. These related algorithms are applicable to other topics, not just ones that are intertwined with biology.2023-10-3163/594,612