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Research Development Newsletter

Funding Opportunities 

Each week RTT emails a newsletter of relevant funding opportunities to the Mines research announcements listserv. Below is a copied list of relevant funding opportunities currently open for submission. If you would like to be added to our weekly newsletter please contact the Research Development team at RTT@mines.edu.

STRIDE Ventures Tech Metal Transformation Challenge

National Science Foundation

Solicitation #: n/a

Deadline: 1/15/2026

Amount: Up to eight teams will receive up to $2M in Stage 1 (10 months) for R&D, up to six teams will advance in Stage 2 (12 months) with up to $2.5M each for market validation, and up to four finalists will earn up to $3M in Stage 3 (12 months) to scale and commercialize their technologies.

The National Science Foundation Directorate for Technology, Innovation and Partnerships (NSF TIP) announced the launch of STRIDE Ventures, a new initiative operated by the Start2 Group to advance innovations that reinforce U.S. technological leadership, economic security and industrial resilience. STRIDE will enable NSF to experiment with new models of innovation funding — connecting researchers to urgent national challenges and accelerating the path from discovery to deployment.

The first funding opportunity of STRIDE Ventures will be the Tech Metal Transformation Challenge, which seeks to strengthen the U.S. supply chain for critical and strategic metals by developing breakthrough technologies. The multiyear, three-stage program was co-designed with and running in parallel to Germany’s SPRIND Tech Metal Challenge. Supported by tiered funding and expert guidance, these programs will advance breakthrough innovations from research and development to market validation, scale-up and deployment.

To support potential applicants, STRIDE Ventures will host a series of informational webinars introducing the Tech Metal Transformation Challenge, its goals, structure and application process. These sessions will provide an opportunity to engage with program staff and ask questions.

  • Webinar 2: Thurs., Dec. 18, 2025, at 2 p.m. EST
  • Webinar 3: Thurs., Jan. 8, 2026, at 2 p.m. EST

Registration is required. Please sign up and receive access details.

Find the solicitation details here

 

Nuclear Science User Facilities (NSUF) Rapid Turnaround Experiment

Department of Energy – Office of Nuclear Energy

Solicitation #: n/a

Deadline: 1/15/2026

Amount: Not specified; work must be completed within 9 months

This award process offers an avenue for researchers to perform irradiation effects studies of limited scope on nuclear energy relevant fuels and materials using NSUF facilities. Completion of RTE projects is expected within 9 months of award. Prospective researchers should request samples from the NSUF Nuclear Fuels and Materials Library. RTE proposals are reviewed and evaluated for technical merit, relevancy and feasibility.

There are several opportunities to learn more about hte RTE call, including:

  • 12/17/2025 at 11:00 am MT: Informational webinar
  • 12/18/2025, 12/19/2025, 1/7/2026 and 1/8/2026: Individual Q&A sessions (must register and schedule in advance)

Learn more about the NSUF RTE Call here

 

Mines & Metals Capacity Expansion – Piloting Byproduct Critical Minerals and Materials Recovery at Domestic Industrial Facilities

Department of Energy – FECM

Solicitation #: DE-FOA-0003583

Deadline: 1/15/2025

Amount: Up to $70M per award

This NOFO invests in American industrial facilities that have the potential to produce valuable critical materials from existing industrial processses and legacy waste streams. Industries such as mining and mineral processing, power generation, coal, oil and gas, specialty metals, and basic materials have the potential to recover valuable materials that will address many of America’s most severe mineral vulnerabilities. The goal of this NOFO is to increase domestic critical material production. There are two topic areas: Mines & Metals Pilots—Coal-Based Industry, and Mines & Metals Pilots—All Industries.

There is an institutionally-coordinated effort underway to respond to this NOFO. If you are interested in being involved, email RTT@mines.edu.

Read the NOFO here

Young Faculty Award (YFA)

Department of Defense – DARPA

Solicitation #: DARPARA2502

Deadline: Executive Summaries are due by 10/15/2025 and proposals are due by 1/20/2026

Amount: Up to $500K over 2 years

The Defense Advanced Research Projects Agency (DARPA) Young Faculty Award (YFA) program aims to identify and engage rising stars in junior research positions in academia and equivalent positions at non-profit research institutions, particularly those without prior DARPA funding, to expose them to Department of Defense (DoD) needs and DARPA’s mission to create and prevent technological surprise for national security. The YFA program will provide high-impact funding to researchers early in their careers to develop innovative new research that enables transformative DoD capabilities. Ultimately, the YFA program is developing the next generation of researchers focused on national security issues. Faculty who are within three years of their tenure date (if tenured) or within 12 years of the receipt of their PhD are eligible.

Read the solicitation here

 

University Transportation Centers (UTC) Program

Department of Transportation

Solicitation #: UTCOPENCOMP2025

Deadline: Letters of Intent are due by 1/19/2026; Applications are due 2/20/2026

Amount: 4 Tier 1 awards will be made for approximately $2M annually for 3 years

The purpose of the UTC Program is for eligible nonprofit institutions of higher education to establish and operate University Transportation Centers. The objectives of each of these Centers are to: 1) Advance transportation expertise and technology in the varied disciplines that comprisethe field of transportation through education, research, and technology transfer activities; 2) Provide for a critical multimodal transportation knowledge base outside of DOT; and 3) Address critical workforce needs and educate the next generation of transportation leaders with respect to the statutory research priorities.

*RTT is encouraging a single LOI and Application to be led by Colorado School of Mines. If you are interested in collaborating, please email Jamal Rostami at rostami@mines.edu and copy RTT@mines.edu.*

Read the UTC NOFO here

NSF Trailblazer Engineering Impact Award (TRAILBLAZER)

National Science Foundation

Solicitation #: NSF 26-502

Deadline: Letters of Intent are due by 1/20/2026; Preliminary Proposals are due by 3/10/2026; Full Proposals are due 7/24/2026

Amount: 5 awards are anticipated for a total amount of $15M

The NSF Trailblazer Engineering Impact Award (TRAILBLAZER) program supports individual investigators who propose novel research projects with the potential to innovatively and creatively address new areas of fundamental or applied research, catalyze development of new industries or capabilities that increase the leadership position for the country, and/or make significant progress towards addressing a national need or grand challenge, particularly in current priority areas including, but not limited to, artificial intelligence (AI), bioengineering, quantum engineering, robotics, and nuclear engineering. TRAILBLAZER will support engineers and scientists who leverage their distinctive track record of innovation and creativity to pursue new research directions that are distinct from their previous or current research areas.

The Emerging Frontiers and Multidisciplinary Activities (EFMA) Office will host an informational webinar in early calendar year 2026 to discuss the TRAILBLAZER program and answer questions about the FY 2026 TRAILBLAZER solicitation. Details on how to join this webinar will be posted on the Directorate for Engineering and EFMA Websites.

Read the TRAILBLAZER solicitation here

Discoveries in Safety Grants

UL Research

Solicitation #: n/a

Deadline: Letters of Intent are due by 1/27/2026

Amount: Up to $200K per year for up to three years

The Discoveries in Safety Grants program supports innovative research aligned with the UL Research mission to address critical safety challenges. The focus areas for the 2026 grant cycle include:

  • Improved respiratory protection options for first responders under toxic smoke conditions
  • Improved recycling technologies to recover critical minerals from energy storage devices
  • Characterization of chemical emissions and residual ash from wildland-urban interface (WUI) fires
  • Mineral fiber emission and transport characterization from wildland-urban interface fires

Find the solicitation details here

Maximizing Investigators’ Research Award (MIRA)

National Institutes of Health – NIGMS

Solicitation #: PAR-26-121

Deadline: 1/27/2026; 5/27/2026

Amount: A PD/PI with more than $400,000 in direct costs from NIGMS research grants will generally receive a MIRA budget that is approximately 12% lower than the PD’s/PI’s average NIGMS research funding levels over recent years (as determined by NIGMS staff). MIRA budgets for New Investigators will generally be $275,000 in annual direct costs.

The Maximizing Investigators’ Research Award (MIRA) provides support for individual investigators for research within the scientific mission of the National Institute of General Medical Sciences (NIGMS) via a single grant to achieve the following:

  • Increase the stability of funding for NIGMS-supported investigators, which could enhance their ability to take on ambitious scientific projects and approach problems more creatively;
  • Increase flexibility for investigators to follow important new research directions within the NIGMS mission as opportunities arise, rather than being bound to specific aims proposed in advance of the studies;
  • More widely distribute funding among the nation’s highly talented and promising investigators to increase overall scientific productivity and the chances for important breakthroughs;
  • Reduce the time spent by researchers writing and reviewing grant applications, allowing them to spend more time conducting research;
  • Reduce the administrative burden associated with a PD/PI managing multiple NIGMS research grants; and
  • Enable PD(s)/PI(s) to devote more time and energy to mentoring junior scientists in a more stable research environment.

This NOFO invites applications from eligible NIGMS-funded investigators and from New Investigators proposing research that is aligned with NIGMS’ scientific mission.

Read the MIRA solicitation here

Collaborative Program Grant for Multidisciplinary Teams

National Institutes of Health

Solicitation #: PAR-23-077

Deadline: 1/27/2026

Amount: Most awards will be between $700K and $900K direct costs per year

This funding opportunity announcement (FOA) encourages Collaborative Program Grant applications from institutions/organizations that propose projects addressing complex and challenging biomedical problems within the mission of NIGMS. Multidisciplinary research teams must have a highly integrated approach for each of their project goals. The Collaborative Program Grant is designed to support research in which funding a team of interdependent investigators to achieve a unified scientific goal offers significant advantages over supporting individual research project grants.

Read NIH FOA

 

Sources Sought for Organization with Capabilities for Advanced Manufacturing Research and Development

Department of Defense – Dept of the Army

Solicitation #: W912CG-26-S-AdvMSSN

Deadline: 1/28/2026

US Army Combat Capabilities Development Command – Soldier Center (DEVCOM SC)  is conducting market research to identify potential college and university laboratories capable of providing, research, development, engineering, and modeling supporting advanced manufacturing (AdvM) technologies, systems, and techniques. The Army seeks to select a civilian institution of higher education that has a proven course curriculum and existing research functions focused on AdvM processes, composite research, additive manufacturing (AM) and design for additive manufacturing (DfAM) as well as an established network with other academic institutions and partnerships with industry to enhance these functions. The institution should have the requisite facilities, security protocols, and faculty to support the Army’s research needs immediately.

Read the Sources Sought Notice here

 

Industrial Technology Validation Program (ITV)

Department of Energy

Solicitation #: n/a

Deadline: 1/29/2026

Amount: $400K split between the technology developer and the industrial host

The US Department of Energy’s (DOE) established the Industrial Technology Validation (ITV)program to provide unbiased assessments of emerging technologies designed to improve operational performance across industrial sectors. In this program, innovative technologies are installed at industrial facilities, their performance is assessed rigorously, and the results are shared publicly to reduce uncertainty about emerging technologies’ performance, fostering broader market confidence and accelerating adoption for successful technologies.

In this program, technology developers and industrial host sites partner with each other, Lawrence Berkeley National Lab (LBNL), and the US Department of Energy (DOE) to evaluate technologies under real-world operational conditions. Technology developers provide the equipment or technology to be tested. Host sites provide the facility where the installation will occur, manage the installation, and provide performance data from both the existing baseline system and the newly installed technology. LBNL analyzes the data and produces a publicly available measurement and verification (M&V) report summarizing the technology’s performance.

Read the ITV guidelines here

 

Mine of the Future – Proving Ground Initiative

Department of Energy – FECM

Solicitation #: DE-FOA-0003390

Deadline: 1/30/2025 (No new Mines team formation at this time)

Amount: Up to $20M per award

The objective of this NOFO is to establish mining technology proving grounds that accelerate novel technology development for the U.S. mining sector. These competitive awards would invest in the infrastructure and technologies to transform mining practices and speed the development of secure and resilient domestic CMM supply networks of the future. This NOFO will enable real-world testing and optimization of the next generation of mining technologies to be deployed at mine sites across the U.S. while offering a training ground for dissemination of skills, technology, practices, and expertise. These proving grounds will be a national resource accessible to all DOE Offices, industry, academia, and other research partners to advance innovation, testing, and workforce development in responsible mining.

There is an institutionally-coordinated effort underway to respond to this NOFO. If you are interested in being involved, email RTT@mines.edu.

Read the NOFO here

 

Payloads and Research Investigations on the Surface of the Moon (PRISM)

NASA

Solicitation #: NNH25ZDA001N-PRISM

Deadline: Step-1 Proposals are due by 11/5/2025; Step-2 Proposals are due by 1/30/2026

Amount: Up to $50M

This NASA Payloads and Research Investigations on the Surface of the Moon (PRISM) program element solicits proposals for two separate investigations that include development and flight of science-driven suites of instruments that will be delivered to the lunar surface by the Commercial Lunar Payload Services (CLPS). In this program element, a “suite” is defined as two or more separate payload elements that work together to achieve the investigation’s objectives. The selected investigations will be delivered to the lunar surface in calendar years 2030 and 2031. A pre-proposal conference will be held on 10/15/2025.

Access the PRISM solicitation here

 

Crystal Palace

Department of Defense – DARPA – Microsystems Technology Office

Solicitation #: DARPA-PA-26-03

Deadline: Abstracts are due by 12/19/2025; Proposals are due by 1/30/2026

Amount: Not specified

The objective of Crystal Palace is to develop new tools and techniques with controls that are local and generalizable, enabling the rapid development of new complex inorganic materials at single crystal quality and at a relevant scale. It is anticipated that these tools and techniques will be able to locally control transport and reaction for material growth. Through novel local control, Crystal Palace will make new complex inorganic single crystal materials with breakthrough properties for the DoW. Materials to be grown in this program will be proposer defined, but proposers are expected to justify their choices based upon anticipated substantial improvement over state-of-the-art material properties and DoW usefulness. Crystal Palace is not focused on computationally discovering materials nor integrating materials into devices. Crystal Palace is specifically focused on direct growth methods for single crystal materials on a relevant substrate for microsystems, i.e., no metal substrates, no material transfer techniques, and no bulk growth.

Read the NOFO here

 

NSF-NIST Bioeconomy Standards Scholars in Residence

National Science Foundation and National Institutes for Standards & Technology

Solicitation #: NSF 25-041

Deadline: White papers are due to NIST prior to 2/1/2026 to allow sufficient time for review; full proposals are due to NSF prior to 4/1/2026

Amount:

  • Faculty/PI: Up to 6 months of salary and benefits, plus up to 20% of that cost for relocation to NIST.
  • Post doc: Up to a year of salary and benefits, plus reasonable moving expenses.
  • Graduate student: Up to 1 year of salary and benefits, plus reasonable moving and/or relocation support – could be full or part time, continuous or broken up.

NSF and NIST are announcing a Bioeconomy Standards Scholar-in-Residence Initiative to catalyze the development of standards and metrics for the bioeconomy. Through the Initiative, researchers (graduate students, postdoctoral fellows, faculty members, and professionals from industry) will have the opportunity to spend dedicated time in a NIST laboratory learning first-hand to develop standards in fields associated with the bioeconomy and biotechnology, and to foster adoption of those standards. These scholars will play a pivotal role in enabling commerce through the development of standards and metrics to help meet the following objectives:

  • Develop machine readable code for one or more standardized protocols.
  • Develop biological or physical objects that enable calibration and/or benchmarking.
  • Enable AI-ready data standardization and integration.
  • Other objectives identified jointly by the applying scholar and NIST.

Read the Dear Colleague Letter here

Human Networks and Data Science (HNDS)

National Science Foundation

Solicitation #: NSF 23-568

Deadline: 2/5/2026 for HNDS-I proposals

Amount: $8M is available annually across all tracks

The Human Networks and Data Science program (HNDS) supports research that enhances understanding of human behavior by leveraging data and network science research across a broad range of topics. HNDS research will identify ways in which dynamic, distributed, or heterogeneous data can provide novel answers to fundamental questions about individual or group behavior. HNDS is especially interested in proposals that provide data-rich insights about human networks to support improved health, prosperity, and security.

Within this program, the Infrastructure Track (HNDS-I) accepts proposals from new applicants. Infrastructure proposals will address the development of data resources and relevant analytic techniques that support fundamental Social, Behavioral and Economic (SBE) research. Successful infrastructure proposals will construct, within the financial resources provided by the award, databases or relevant analytic techniques and produce a finished product that will enable previously impossible data-intensive research in the social sciences. The databases or techniques should have significant impacts, either across multiple fields or within broad disciplinary areas, by making possible new types of data-intensive research in the SBE sciences.

Read the HNDS solicitation here

High-efficiency Nitrogen Oxidation (HNO3)

Department of Defense – DARPA

Solicitation #: HR001126S0005

Deadline: Abstracts are due by 12/18/2025; Proposals are due by 2/5/2026

Amount: Not specified

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals inthe foundational technologies to enable high-rate, energy efficient, decentralized nitric acidmanufacturing to protect critical supply chains in the defense industrial base and redefineenergetics manufacturing in contested logistics environments.

Read the HNO3 NOFO here

BioStabilization Systems (BoSS)

National Institutes of Health – ARPA-H

Solicitation #: ARPA-H-SOL-26-136

Deadline: Solicitation Summaries for Performers are due 2/19/2026

Amount: Not specified

The BioStabilization Systems (BoSS) program aims to transform how live cell-based therapies are stabilized, manufactured, and distributed. At its core, BoSS addresses a foundational bottleneck in the delivery of advanced cell and gene therapies (CGTs): the critical dependence on ultra-cold conditions (-80 to -196˚C) for storage and transport. BoSS will yield a bioprocessing system that enables scalable production of thermally stable cells, paving the way for a new era of efficient and resilient manufacturing and distribution of biologics without any need for cold storage. BoSS-developed technologies will also accelerate many other avenues in biotechnology that directly impact healthcare, including bio-surveillance, regenerative medicine, large-scale genetic testing, blood product supply, and wound repair, in addition to improving access to a wide range of existing biotherapeutics. A Proposer’s Day will be held on 1/29/2026.

Read BoSS Innovative Solutions Opening here

Advanced Industries Proof of Concept and Early Stage Capital and Retention Grants

State of Colorado Office of Economic Development and International Trade (OEDIT)

The OEDIT Advanced Industries Grant Program is now accepting applications through February 26, 2026, for two programs.  

Advanced Industries Proof of Concept Grant:

The Advanced Industries Proof of Concept Grant provides funding to help Colorado research institutions speed up applied research in advanced industries and commercialize products and services with the private sector. Projects can receive up to $150,000 in grant money and require one match dollar for every three state dollars requested. The match must be cash and available at the time of the award.  You cannot apply if you have an active POC grant with the State of Colorado. 

The online application must be completed and the Mines RTT Office notified at RTT@mines.edu by 5pm on February 19, 2026. The application will be reviewed and then submitted to the CO Economic Development and International Trade office before the February 26 deadline.

The application process requires an initial step taken by the RTT Office to approve applicants, after which OEDIT can create access to the online portal for you. To initiate this step, please email RTT@mines.edu and include:

  • Your name and title
  • Your project title

Please be aware that you will also need to work with the Office of Research Administration for the budget form. 

Advanced Industries Early-Stage Capital and Retention Grant:

This opportunity is for early-stage start-ups. This grant helps Colorado-based advanced industries technology businesses develop and commercialize advanced technologies that will be created or manufactured in Colorado. If you have or are working with a start-up and would like to apply, this requires two match dollars (in cash) for every one state dollar requested for up to $250,000. For this opportunity, applicants apply directly to OEDIT and do not need to go through the RTT Office.

Genetic Medicines and Individualized Manufacturing for Everyone (GIVE)

National Institutes of Health – ARPA-H

Solicitation #: ARPA-H-SOL-25-129

Deadline: Solution summaries are due by 12/19/2025. Full proposals are due by 2/27/2026.

Amount: Not specified

The Advanced Research Projects Agency for Health (ARPA-H) Genetic Medicines And Individualized Manufacturing For Everyone (GIVE) Program aims to accelerate biomanufacturing equipment and process innovation, digital transformation, next generation therapies, and commercial adoption all at once. GIVE seeks to harness human-machine collaboration, eliminate scale-up costs, and drive toward a fundamentally different future state – a state where biomanufacturing is localized, accessible, and individualized. Details for the ARPA-H GIVE Program Proposer’s Day are currently being finalized. A Special Notice with the event information and logistics will be forthcoming.

Read the GIVE Program Innovative Solutions Opening here

 

FY26 Distinguished Early Career Program

Department of Energy – Idaho Operations Office

Solicitation #: DE-FOA-0003540

Deadline: 3/3/2026

Amount: $800K over 5 years

The Distinguished Early Career Program NOFO provides stable support for early career faculty to form the impactful research groups, innovative lines of inquiry, educational approaches, and critical new research directions that will drive the next generation of nuclear energy innovation.

Distinguished Early Career Program NOFO Part 1

Distinguished Early Career Program NOFO Part 2

 

 

NSF/CASIS Transport Phenomena Research at the International Space Station to Benefit Life on Earth

National Science Foundation

Solicitation #: NSF 25-529

Deadline: Feasibility Review Form is due by 1/12/2026. Invited proposals are due by 3/4/2026.

Amount: Up to $4M for up to 4 years

The Division of Chemical, Bioengineering, Environmental, and Transport Systems (CBET) and the Division of Civil, Mechanical, and Manufacturing innovation (CMMI) in the Engineering Directorate (ENG) and the Division of Materials Research (DMR) in the Directorate for Mathematical and Physical Sciences (MPS) of the U.S. National Science Foundation (NSF) are partnering with The Center for the Advancement of Science in Space, Inc. (CASIS) to solicit research projects in the general fields of fluid dynamics, particulate and multiphase processes, combustion and fire systems, thermal transport processes, nanoscale interactions, manufacturing methods that employ any of those transport phenomena, and resulting metallic materials, metal nanostructures and ceramic materials that can utilize the International Space Station (ISS) National Lab to conduct research that will benefit life on Earth. Only entities that qualify as “U.S. Persons” under 22 U.S. Code §6010, including academic investigators, non-profit independent research laboratories and academic-commercial teams are eligible to submit proposals.

Read the NSF/CASIS solicitation here

 

ACS Petroleum Research Fund

American Chemical Society

Solicitation #: n/a

Deadline: 3/6/2026

Amount: For faculty applying for a New Directions grant or a Doctoral New Investigator grant, maximum request is $110K over 2 years

The Petroleum Research Fund is an endowed fund, managed by the American Chemical Society that supports fundamental research directly related to petroleum or fossil fuels at nonprofit institutions (generally colleges and universities) in the United States and other countries. ACS Petroleum Research Fund (ACS PRF) grants are intended as seed money, to enable an investigator to initiate a new research direction. The investigator should not have published or received financial support from another funding agency for the proposed research. Proposals must be for fundamental research in “the petroleum field,” which is defined in our founding document as “petroleum, natural gas, coal, shale, tar sands and like materials.”

Learn more about the award guidelines at their website

 

Mechanisms for Amplification of fusion Reaction Rates in Solids (MARRS)

Department of Defense — DARPA

Solicitation #: HR00112S0007

Deadline: Abstracts are due by 1/26/2026; Proposals are due by 3/12/2026

Amount: Not specified

Based on new theoretical predictions and new data suggesting high fusion reaction rates may be  possible at relatively low reaction temperatures in solids (< ~2,000 degrees Kelvin or < ~0.2 eV), the MARRS program will explore how much we can scale solid-state fusion for new applications. The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals in exploring and implementing mechanisms that amplify and increase the rates of nuclear fusion reactions in solids at and near Room Temperature. Proposed research should investigate innovative approaches that enable revolutionary advances in science, devices, or systems.

Read the MARRS solicitation here

Autonomous Interventions and Robotics (AIR)

National Institutes of Health – ARPA-H

Solicitation #: ARPA-H-SOL-26-146

Deadline: Solution Summaries are due by 1/26/2026; Full Proposals are due 3/30/2026

Amount: Not specified

The Autonomous Interventions and Robotics (AIR) program aims to catalyze the developmentof autonomous robotic surgery—an intervention during which a robot performs part, or all, of the procedure without direct human input. AIR encompasses two (2) technical areas: Technical Area 1 (TA1)—endovascular robotics, and Technical Area 2 (TA2)—microbots.Technical Area 1 comprises sub-areas TA1-A—endovascular robotic systems and TA1-B—endovascular simulation environment.

A Proposer’s Day, with both in-person and virtual options, will be held on December 16, 2025, in Rockville, Maryland. Learn more and register here.

Read the NOFO here

 

FY26 Scientific Infrastructure Support for Consolidated Innovative Nuclear Research

Department of Energy – Idaho Operations Office

Solicitation #: DE-FOA-0003541

Deadline: 4/9/2026

Amount: $250K over 1 year

The goals of this NOFO include: (1) Supporting, maintaining, or enhancing an institution’s capacities to attract and teach high quality students interested in nuclear energy-related studies; (2) building an institution’s research or education capabilities; and (3) enhancing an institution’s capabilities to perform R&D that is relevant to NE’s broader mission. Topic Area 1 is for Reactor Upgrades and Topic Area 2 is for General Scientific Infrastructure. Mines is eligible to apply under Topic Area 2.

Scientific Infrastructure Support for CINR NOFO Part 1

Scientific Infrastructure Support for CINR NOFO Part 2

 

Research Opportunities in Space and Earth Sciences 2025 (ROSES-2025)

NASA Solicitation # NNH25ZDA001N
Deadline: Open through 5/31/2026
Amount: Available funding for the entire omnibus NOFO is approximately $125M-$150M, contingent on funding
Approximately 35 proposal opportunities comprise this “ROSES” Solicitation that supports a wide range of research relevant to NASA’s Science Mission Directorate including: theory about what will be observed; the development of technology to make observations to test those theories; collection of samples and data from land, sea, air and space; analysis of samples and data collected; laboratory measurements of samples and fundamental parameters to compare to data; and modeling using the data, resulting in a better understanding of the real-world implications of all of the above, for e.g., effects of natural disasters on Earth and the exploration of space. Refer to the links within the omnibus announcement for all proposal opportunities and their individual due dates as well as common requirements for all proposal opportunities.
Read ROSES-25

 

FY25 Office of Naval Research Science, Technology, Engineering, and Mathematics (STEM) Education and Workforce Program

Department of Defense – ONR Solicitation # N0001425SF006
Deadline: 6/30/2026
Amount: Not specified

This NOFO will support formal or informal education that is primarily focused on physical and natural sciences, technology, engineering, social sciences, and mathematics disciplines, topics, or issues (including environmental science education or stewardship). STEM education programs and activities that could be supported by this NOFO include one or more of the following as the primary objective:

  • Develop learners’ knowledge, skill, or interest in STEM.
  • Attract students to pursue certifications, licenses, or degrees (two-year degrees through post-doctoral degrees) or careers in STEM fields.
  • Provide growth and research opportunities for post-secondary, college and graduate students in STEM fields, such as working with researchers or conducting research that is primarily intended to further education.
  • Improve mentor/educator (K-12 pre-service or in-service, post-secondary, and informal) quality in STEM areas.
  • Improve or expand the capacity of institutions to promote or foster STEM fields.
Read the ONR STEM Education solicitation

 

FY 2026 Continuation of Solicitation for the Office of Science Financial Assistance Program

Department of Energy – Office of Science

Solicitation #: DE-FOA-0003600

Deadline: Applications are accepted on a rolling basis through 9/30/2026. Pre-applications are optional/encouraged

Amount: A total of $500M is expected to be available. Historically, individual awards have ranged from $5K to $5M for a period of 6 months to five years.

The Office of Science (SC) of the Department of Energy (DOE) hereby announces its continuing interest in receiving applications for support of work in the following program areas: Advanced Scientific Computing Research, Basic Energy Sciences, Biological and Environmental Research, Fusion Energy Sciences, High Energy Physics, Nuclear Physics, and Isotope R&D and Production. This NOFO is the DOE’s annual open solicitation that covers all research areas in SC and is open throughout the Fiscal Year. Any research within SC’s Congressionally authorized mission may be proposed under this NOFO.

Read the solicitation here

 

DoD STEM National Defense Education Program (NDEP)

Department of Defense Solicitation # HQ003423NFOEASD01
Deadline: Open through 2/8/2028
Amount: Not specified
DoD seeks innovative proposals to advance STEM education, outreach, and workforce development. This announcement supports a wide range of initiatives including STEM education and outreach; manufacturing engineering education and workforce development aligned with DoD’s critical technology areas (e.g., microelectronics, AI, autonomy, biotech). Applicants must first submit a white paper in response to a specific NFO amendment or Industry/Opportunity Day. Selected applicants will be invited to submit full proposals.
Read NOFO

 

Research and Development (RAD) Directed Energy (RD) University Assistance Instruments

DOD Air Force Research Lab Solicitation # DO-FOA-0003418
Concept Papers: 7/18/2029
Amount: $49M
The Air Force Research Laboratory Directed Energy Directorate (RD) is the Department of the Air Force’s Center of Expertise for directed energy and optical technologies. The Directorate develops and transitions technologies in four core technical competencies: Laser Systems, Directed Energy and Electro-Optics for Space Superiority, High Power Electromagnetics, and Weapons Modeling, Simulation, and Analysis. This five-year, open FOA is for soliciting research applications for Basic, Applied, and Advanced Research in the Core Technical Competencies (CTCs) described above. Multiple awards of assistance instruments are anticipated with periods of performance ranging from one to five years.
Read Solicitation

 

Signals Intelligence Focused Technologies for Exploitation and Reporting (SIFTER)

Department of Defense – Dept of the Air Force

Solicitation #: FA875024S7007

Deadline: White papers accepted through 9/28/2029

Amount: Total funding for this ARA is approximately $99.9M. Individual awards will not normally exceed 60 months with dollar amounts normally ranging from $1M to $5M.

Through this ARA, the Air Force seeks innovative research to investigate algorithms, methodologies, and techniques for the demonstration and evaluation of enhanced signal information exploitation, dissemination, and analytics of existing and emerging adversarial systems. Areas of emphasis include 1) onboard processing enhancements of manned and unmanned Intelligence, Surveillance, and Reconnaissance (ISR) platforms; 2) high speed signal detection and prosecution technology demonstration, 3) cross domain multi-sensor/multi-platform data analytics, and 4) Open System Architecture (OSA) compliance for demonstration in operationally relevant environments.

Read the SIFTER ARA here

 

Advanced Cyber Effects for Strategic Operations (ACESO)

Department of Defense – AFRL Solicitation # FA8750-25-S-7005
Deadline: White papers are accepted any time through 7/10/2030
Amount: Individual awards will range from $10M to $60M and will not exceed 60 months in duration
The Air Force Research Laboratory is soliciting white papers under this Advanced Research Announcement (ARA) to research, design, develop, test, evaluate, implement, and transition Command, Control, Communications, Computers, and Intelligence (C4I) and Cyber technologies.  The Air Force Research Laboratory’s (AFRL’s) strategic vision for cyber superiority is to ensure the scientific research and development being conducted, plays an integral role in AFRL’s mission.  AFRL’s mission is to lead the discovery, development, integration, and transition of affordable warfighting technologies for our air, space, and cyberspace force.  These capabilities will explore, prototype, and demonstrate high-impact, affordable and game-changing technologies giving the air, space, and cyberspace forces the competitive advantage needed to protect and defend the nation. As the Air Force is an air component to a Joint Force Commander (JFC), capabilities will further expand and enhance full spectrum cyber operations, cyber mission assurance, resiliency capabilities, as well as support effects on the Cyber Adversary via strategic operations within the Department of Defense (DoD), the United States, Intelligence Community (IC), and coalition cyber platforms.
Read the ACESO ARA

 

Applications for Cyber Warfare: Genesis

Department of Defense – Dept of the Air Force

Solicitation #: FA8750-25-S-7006

Deadline: White papers accepted through 9/30/2030

Amount: Total funding for this ARA is approximately $999M. Individual awards will not normally exceed sixty (60) months with dollar amounts normally ranging from $10M to $50M.

The purpose of this Advanced Research Announcement (ARA) is to research, design, develop, implement, and refine next-generation cyber warfare capabilities to advance the nation’s ability to prepare and fight wars as well as to build enduring advantages in Cyberspace.  This includes both cyber platforms and cyber weaponry.

Read the ARA here

 

NSF National Innovation Corps Teams (NSF National I-Corps (TM) Teams) program

National Science Foundation

Solicitation #: NSF 25-549

Deadline: Proposals accepted any time

Amount: Up to $50K for 12 months

The purpose of the NSF National I-Corps Teams program is to provide NSF-funded researchers additional support in the form of entrepreneurial education, mentoring, and funding to accelerate the translation of knowledge derived from foundational research into emerging products, processes, and services that may attract subsequent third-party funding.The outcomes of NSFNational I-Corps Teams’ projects are threefold: 1) a decision on a clear path forward based on an assessment of the business model, 2) substantial first-hand evidence for or against product-market fit, with the identification of customer segments and corresponding value propositions, and 3) a narrative of a technology demonstration for potential partners.

Proposers must have either 1) received a prior award from NSF in a scientific or engineering field relevant to the proposed innovation that is currently active or that has been active within five years from the date of the NSF National I-Corps Teams proposal submission or 2) have participated in a NSF Regional I-Corps Training program hosted by an NSF I-Corps Hub and have a letter of recommendation signed by a senior member of the NSF Regional I-Corps program staff.

Read the solicitation here

 

NSF STEM K-12

National Science Foundation

Solicitation #: NSF 25-545

Deadline: Proposals accepted anytime

Amount: Most awards will range from $25K to $750K

The NSF STEM K-12 program in the Division of Research on Learning in Formal and Informal Settings (DRL) in the Directorate for STEM Education (EDU) supports fundamental, applied, and translational research that advances STEM teaching and learning and improves understanding of education across the human lifespan and a range of formal and informal settings. Investigators who would have normally submitted to the following archived programs are encouraged to submit to this solicitation: Advanced Informal STEM Learning (AISL), Computer Science for All (CSforAll), Discovery Research PreK-12 (DRK-12), and Translation and Diffusion (TD).

Read NSF K-12 Solicitation

 

Measurement Science and Engineering (MSE) Research Grant Programs

Dept of Commerce – NIST Solicitation # 2025-NIST-MSE-01
Deadline: Proposals are accepted on a rolling basis
Amount: Varies by grant program
The purpose of the Measurement Science and Engineering (MSE) Research NOFO is to support activities that develop, expand, strengthen, or sustain NIST partnership programs and/or support the conduct of research or a recipient’s portion of collaborative research in a variety of areas including, but not limited to: Metrology; Standards; Nanotechnology; Artificial Intelligence; Advanced Communications; Advanced Manufacturing; Promotion of U.S. innovation and industrial competitiveness; Measurements in Sciences; Neutron Research; and enhancing coordination of the U.S. Standards System with government and private sector organizations. This NOFO seeks applications for measurement science and standards research in the areas described by each MSE Grant Program (detailed in the NOFO), which will support the development of a general population that understands and appreciates measurement science and standards.
Read MSE Research Grant NOFO

 

Marine Geology and Geophysics (MG&G)

National Science Foundation Solicitation # PD 17-1620
Deadline: Proposals are accepted anytime
Amount: Not specified. Average past awards range from $300K-$400K

The Marine Geology and Geophysics Core Program supports research on all aspects of the geology and geophysics of the present ocean basins and margins, as well as those of the Great Lakes. The Program supports science that includes:

  • Structure, composition, tectonics, and evolution of the oceanic lithosphere
  • Paleoceanography, paleoclimate, and sea level change
  • Submarine volcanology, petrology and geochemistry of the oceanic crust and upper mantle lithosphere
  • Marine hydrogeology, water-rock interaction, seeps and gas hydrates
  • Hydrothermal venting and in situ fluid processes, and associated geochemistry
  • Geochemical indicators of life operating below the seafloor
  • Marine sedimentology, stratigraphy, sediment transport, and diagenesis
  • Mid-ocean ridge spreading, back-arc rifting, transform processes, and ocean island/seamount formation and evolution
  • Submarine components of subduction zone systems and passive margins
  • Marine geohazards (e.g., earthquakes, faulting, mass wasting, geological aspects of tsunamis)
  • Coastal processes (e.g., geological aspects of hurricanes, sea-level change, erosion, offshore deposition)
Read MG&G Solicitation

 

Mines Membership to the Medical Technology Enterprise Consortium Opens New Funding Opportunities

The Medical Technology Enterprise Consortium (MTEC) is a 501(c)(3) biomedical technology consortium that is internationally-dispersed, collaborating with multiple government agencies with the U.S. Army Medical Research and Development Command. The consortium focuses on the development and delivery of innovative medical technologies that protect, treat, and optimize the health and performance of U.S. military personnel and civilians. As a member organization, Mines faculty may apply to any of their open solicitations, which are announced throughout the year. Solicitation topics vary but may be applicable to those in quantitative biosciences and engineering, computer science, materials science, chemistry, physics, and other disciplines. Check their website throughout the year for current and upcoming solicitations.

See current and upcoming solicitations

 

Colorado School of Mines Accelerator Fund Accepting Proposals Year-Round

The Colorado School of Mines Office of Research and Technology Transfer is soliciting applications for commercialization projects based on Mines intellectual property. The purpose is to provide funding to Mines’ researchers who have made progress moving their invention into the commercial market and are interested in continuing the process. It is also to serve as pre-seed funds before applying for investment funding, including Mines Venture Fund. This fund has been made possible by funding from the Colorado School of Mines Foundation and the State of Colorado’s Advanced Industry Program. Projects submitted to this competition should be short-duration (up to one year) and low-cost ($50K maximum) go-to-market projects. If you have questions, please reach out to RTT, at RTT@mines.edu

Read Solicitation

 

Staff Research Program

Department of Defense – Dept of the Army Solicitation # W911NF25S0007
Deadline: Proposals are accepted on a rolling basis through June 2, 2030
Amount: Not specified
The purpose of the Staff Research Program is to enable Army Research Office (ARO) scientific staff to maintain and expand professional competence in support of fulfilling the ARO mission through the conduct of hands-on, basic research. The staff research will be performed collaboratively with institutions external to ARO. Staff research efforts will involve scientific study directed toward advancing the state-of-the-art or increasing knowledge and scientific understanding in engineering, physical, life and information sciences, when there is an intersection with the interests and capabilities of the participating external institutions in these basic research areas.
Read Army Staff Research Program Announcement

 

NSF-DFG Lead Agency Opportunity on Collaborative Research on Climate Change (NSF-DFG GEO)

National Science Foundation/German Research Foundation Solicitation # NSF 23-113
Deadline: Expressions of Interest (recommended first step) and Proposals are accepted on a rolling basis
Amount: Not specified
The Directorate for Geosciences (GEO) of the National Science Foundation (NSF) and the German Research Foundation (DFG) Geosciences are pleased to announce an NSF/GEO-DFG/Geosciences Lead Agency Opportunity. The goal of this opportunity is to reduce barriers to working internationally. Through a Lead Agency model, GEO and DFG/Geosciences will address these issues by allowing U.S. and German researchers to submit a single collaborative proposal that will undergo a single review process. NSF/GEO participating programs include Division of Atmospheric and Geospace Sciences, Division of Earth Sciences, Division of Ocean Sciences, and the Office of Polar Programs.
Read the Dear Colleague Letter from NSF

 

Mind, Machine and Motor Nexus (M3X)

National Science Foundation Solicitation # PD 25-058Y
Deadline: Proposals accepted anytime
Amount: Not specified. Past awards have ranged from $200K to $1M.
The Mind, Machine, and Motor Nexus (M3X) program supports fundamental research that enables intelligent engineered systems and humans to engage in bidirectional interaction in a physics-based environment, to enhance and ensure safety, productivity, and well-being. While proposals are not required to address all aspects of the interaction, they must propose significant contributions to at least one of the following areas: Conceptual frameworks and theoretical modeling; Dynamic interaction analysis and simulation; and Innovative technologies for enhanced interaction. The M3X program strongly encourages proposals that aim to establish new perspectives and paradigms across one or more of these three areas.
Read Solicitation

 

Seeding Critical Advances for Leading Energy Technologies with Untapped Potential (SCALEUP) Ready

Department of Energy – ARPA-E Solicitation # DE-FOA-0003467
Deadline: Applications are accepted any time and the NOFO will remain open until closed or modified
Amount: $50M in total funding available
The Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP) Ready Notice of Funding Opportunity (NOFO) provides a vital mechanism for the support of innovative energy R&D that complements ARPA-E’s primary R&D focus on early-stage transformational energy technologies that still require proof-of-concept. An enduring challenge to ARPA-E’s mission is that even technologies that achieve substantial technical advancement under ARPA-E support face significant remaining technical and commercial risks upon completion of an award’s funding period, and thus are at risk of being stranded in their development path once ARPA-E funding ends. Experience across ARPA-E’s diverse energy portfolios, and input from a wide range of investors and industry stakeholders, indicates that pre-commercial “scaling” projects are critical to establishing that performance and cost parameters can be met in practice for these potentially transformative technologies. These pre-commercial scaling projects aim to translate the performance achieved at bench scale to commercially scalable versions of the technology, integrate the technology with broader systems, provide extended performance data, and validate the manufacturability and reliability of new energy technologies. Success in these scaling projects should enable industry, investors, and partners to justify the substantial commitments of financial resources, personnel, manufacturing facilities, and materials necessary to subsequently deploy the technologies at commercial scale. The objective of SCALEUP Ready is to support the scaling of high-risk and potentially disruptive new technologies across the full spectrum of energy applications. This NOFO focuses only on scale-up and pre-pilot projects of promising technologies that ARPA-E has previously funded – following highly competitive selection processes – and for which the scale-up award would substantially build upon innovations achieved under the original ARPA-E award.
Read Solicitation

 

 

Infrastructure Systems and People (ISP)

National Science Foundation Solicitation # PD 25-342Y
Deadline: Proposals accepted anytime
Amount: Not specified
The Infrastructure Systems and People (ISP) program will support fundamental research on the design, optimization, sustainability and resilience of infrastructure systems during normal operation and extreme events, such as natural hazards, to serve community needs. The program particularly encourages interdisciplinary and multidisciplinary exploration that will open new research frontiers and significantly broaden and transform relevant research communities. The program welcomes research that addresses novel system integration, user-inspired system and service design, data analytics, and socio-technical studies focused on engineering and system innovation during normal and extreme conditions. The program also values innovative research efforts focused on collecting, standardizing, and sharing large-scale databases of real-world infrastructure systems and people-infrastructure interactions during normal and extreme operating conditions, which can be instrumental in providing benchmarks for model verification and validation and for advancing future research innovation in ISP.  Proposers are actively encouraged to email a one-page project summary to the ISP Program Officers before submitting a full proposal for guidance on whether the proposed research topic falls within the scope of the ISP program.
Read Solicitation

 

Life and Environments Through Time (LET)

National Science Foundation Solicitation # NSF 25-517
Deadline: Proposals accepted anytime
Amount: A total of $14M is available for 50 awards
This is a new solicitation arising from a realignment of the Division of Earth Science’s disciplinary funding programs. The Life and Environments Through Time (LET) program supports research that advances knowledge about the patterns and processes relating to the origin and evolution of Earth’s climate, environments, life, and sedimentary record. This research takes place at the molecular, local, regional, and global scales from the Archean Eon through the Holocene epoch. LET-supported research can be useful for predicting and planning for future global change, and for the maintenance and security of ecosystem services and human societies.
Read Solicitation

 

Water, Landscape, and Critical Zone Processes (WaLCZ)

National Science Foundation Solicitation # NSF 25-519
Deadline: Proposals accepted anytime
Amount: A total of $24M is available for 60-80 awards
This is a new solicitation arising from a realignment of the Division of Earth Science’s disciplinary funding programs. The Water, Landscape, and Critical Zone Processes program supports research on the Earth’s near-surface environment and how that environment responds to change. The Program focuses on the complex interplay amongst and between hydrologic, geomorphic, and geochemical processes and how they regulate the structure and function of the Earth’s near surface. These processes drive weathering and soil development, control water availability and quality, and help regulate the Earth’s climate system, all of which are important for natural resource sustainability and mitigation of natural hazards. It is expected that the research funded in this program will advance fundamental knowledge in Earth surface processes, leading to transformational discoveries in Earth Sciences.
Read Solicitation

 

Structure and Physics of the Solid Earth (SPSE)

National Science Foundation Solicitation # NSF 25-518
Deadline: Proposals accepted anytime
Amount: A total of $22M is available for 60-75 awards
This is a new solicitation arising from a realignment of the Division of Earth Science’s disciplinary funding programs. The Structure and Physics of the Solid Earth Program (SPSE) aims to advance fundamental knowledge about the ongoing dynamical processes over the age of the Earth that evolve the structure of planet Earth and underpin geohazards. SPSE supports research at all temporal and spatial scales, from the Earth’s core to its crust. Through laboratory, field, theoretical, and computational studies, the program encompasses a wide range of disciplines including structural geology, tectonics, and geophysics. Research in these areas can help improve our understanding of natural hazards including earthquakes and mass flows, as well as Earth’s formation and its magnetic field. 
Read Solicitation

 

Foundational Research in Robotics (FRR) Focus on Agricultural Robotics

National Science Foundation/USDA Solicitation #

DCL: 24-080

PD 20-144Y

Deadline: Proposals accepted any time
Amount: Past awards range from $300K to $1M
The Foundational Research in Robotics (FRR) program, jointly led by the CISE and ENG Directorates, supports research on robotic systems that exhibit significant levels of both computational capability and physical complexity. The program welcomes research that considers inextricably interwoven questions of intelligence, computation, and embodiment. Projects may also focus on a distinct aspect of intelligence, computation, or embodiment, as long as the proposed research is clearly justified in the context of a class of robots. In particular, NSF has issued a Dear Colleague Letter in partnership with the USDA National Institute of Food and Agriculture (NIFA) to encourage proposals to the FRR program that advance foundational research in agricultural robotics.

Read Dear Colleague Letter

 

 

Natural Climate Solutions (NCS) Implementation

Allen Family Philanthropies

Deadline: Letters of Intent are due by 1/15/2026

Amount: A total of $10M is available for 6-7 awards; $1M – $1.5M per award

Natural Climate Solutions (NCS) are nature-based actions that protect, restore, and improve management of forests, wetlands, grasslands, oceans, and agricultural lands, mitigating climate impacts by working with natural ecosystems. This new RFP seeks to support efforts to develop science and technology solutions to accelerate NCS implementation in the United States. Allen Family Philanthropies will host an informational webinar on December 9, 2025 at 9 am PT with a live Q&A about this opportunity. You can register to attend the webinar here.

Learn more about the grant and how to apply on the program website

Scientific Software Research Faculty Award

Simons Foundation

Deadline: Letters of Intent are due by 1/21/2026

Amount: A Scientific Software Fellowship provides five years of salary support for the awardee’s academic-year salary and fringe benefits, whether normally paid over 9 or 12 months, as follows: 100 percent salary for each of the first two years and then 50 percent each year for next three years. For the last three years, the host university is expected to provide the other 50 percent of salary support each year through existing department channels. The fellowship will also provide a yearly $50,000 research allowance for the awardee, plus indirect costs for the host institution (limited to 20 percent of the modified total direct costs).

The Simons Foundation invites applications for funding to support new research professor positions (e.g., “clinical professor,” “professor of practice” or “research professor,” the titles and roles depending on the university) in existing academic departments (the “host institutions”) to be filled by scientific software-focused researchers. The SSRF Award will support researchers who have a strong track record of leadership in scientific software development. The aim of this program is to stimulate the development and maintenance of core scientific software infrastructure in academic environments through creating a new, long-term, faculty-level career path.

Learn more about the grant and how to apply on the program website

Simons Foundation Targeted Grants in Mathematics & Physical Sciences

Deadline: Letters of Intent are accepted anytime
Amount: Provides funding for up to five years. The funding level and duration is flexible and should be appropriate based on the type of support requested in the proposal. There is no recommended or assumed funding level for this program.
The Simons Foundation’s Mathematics and Physical Sciences (MPS) division invites applications for its Targeted Grants in MPS program. The program is intended to support high-risk theoretical mathematics, physics and computer science projects of exceptional promise and scientific importance on a case-by-case basis. PIs and co-Investigators must have a Ph.D. and a tenure-track or tenured position at said institutions or centers at the time of application. There are no citizenship or department requirements for PIs. Indirect costs are limited to 20 percent of applicable direct costs.
Read the full guidelines on the Simons Foundation website

Current Calls for Expressions of Interest

Hearing from you that you are interested in a limited submission opportunity helps us determine whether a full internal competition will be needed. The only information you typically need to provide in an expression of interest is your name and department information (and that of your team, if applicable) and your tentative project title. All applications are accepted through InfoReady.

 

G. Harold and Leila Y. Mathers Foundation Grant Award Program – Spring 2026 Cycle

Harold and Leila Y. Mathers Foundation

Internal Deadline: 1/12/2026

Limit: 3

The Mathers Foundation supports pivotal scientific research that advances knowledge, enhances human health, and fosters innovation. The foundation empowers researchers whose work holds the greatest promise for advancing mankind and medicine, driving meaningful, long-term contributions to science and society. The Foundation has recently, and with the advent of newer investigative methodologies, technology, and tools, embraced innovative translational research proposals in addition to basic science research. They are focused on biomedical with an emphasis on health and the life sciences. Immunology, Microbiome, Structural Biology, Cellular Physiology, Cancer Biology, Genetics, Genomics, Microbiology & Infectious Diseases, Stem Cell Biology, Neuroscience, etc., are some noteworthy examples of current research support.

Read full guidelines and apply in InfoReady 

Pivot Search BAA’s search – https://www.grants.gov/search-results-detail/352238

The following list of opportunities is organized by agency.

DOT

Unmanned Aircraft Systems (UAS) Office Broad Agency Announcement

Department of Transportation – FAA

Solicitation #: 697DCK-25-R-00278

Deadline: White papers accepted through 9/30/2028

Amount: Total funding cap is $24M across FY 2025-2028

The FAA Unmanned Aircraft Systems (UAS) Broad Agency Announcement (BAA) funds research, testing, and demonstration projects that advance the safe integration of UAS (drones) into the National Airspace System (NAS).

The program supports non-system-specific development and applied research that improves the safety, efficiency, and operational readiness of UAS technologies. Funding is provided on a cost-sharing basis (1:1 match), where the FAA pays up to 50% of total project costs. Awards are made through contracts, primarily for projects that include demonstration, validation, or testing at one of the FAA-designated UAS Test Sites.

Funding priorities fall within ten Focus Areas:

  1. UAS Traffic Management (UTM)
  2. Beyond-Visual-Line-of-Sight (BVLOS) Operations
  3. UAS Integration and Industry Consensus Standards
  4. Electronic Conspicuity (EC)
  5. Noise and Environmental Impacts
  6. Command and Control (C2) Link Technologies
  7. Detect and Avoid (DAA) Technologies
  8. UAS Collision Safety
  9. Autonomous Operations
  10. Advanced Air Mobility (AAM)

Read the UAS BAA here

DHS

2024 Department of Homeland Security (DHS) Directorate of Science & Technology Long Range BAA

Department of Homeland Security

Solicitation #: DHS_ST_LRBAA_24-01

Deadline: Submissions are accepted through 5/31/2029

Amount: Not specified

The purpose of this LRBAA is to fund scientific and technical projects across a spectrum of science and engineering disciplines that significantly improve or increase a capability to the Department’s operational environment and the Homeland Security Enterprise (HSE).The three-step process to apply begins with an Industry Engagement Submission, during which Scientific/Component Subject Matter Experts (SME) and Program Managers (PM) evaluate submissions to the DHS S&T OIP portal from interested sources in the scientific and industrial community to identify a broad range of qualified offerors. The current six key mission areas are:

  1. Counter Terrorism and Homeland Security Threats; (CTHOM)
  2. Secure U.S. Borders and Approaches (BORAP);
  3. Secure Cyberspace and Critical Infrastructure (CYBCI);
  4. Preserve and Uphold the Nation’s Prosperity and Economic Security (PROES);
  5. Strengthen Preparedness and Resilience (PRRES); and
  6. Champion the DHS Workforce and Strengthen the Department (WORDT).

Read the DHS BAA

DOD

 

Information Innovation Office (I2O) Office-Wide

Department of Defense – DARPA

Solicitation #: HR001126S0001

Deadline: Abstracts are accepted through 11/1/2026

Amount: Not specified

This Broad Agency Announcement (BAA) seeks revolutionary research ideas for topics not being addressed by ongoing I2O programs or other published solicitations. Potential proposers are highly encouraged to visit the I2O technical office page (https://www.darpa.mil/about/offices/i2o) to view current and upcoming I2O programs and solicitations in order to avoid proposing efforts that duplicate existing activities or that are responsive to other published I2O solicitations.

Link to I2O BAA

2025 ERDC Broad Agency Announcement

Department of Defense – Dept of the Army

Solicitation #: W912HZ-25-BAA-01

Deadline: Pre-proposals may be submitted anytime

Amount: Not specified

The U.S. Army Corps of Engineers (USACE) Engineer Research and Development Center (ERDC) has issued this continuously open announcement for research and development concepts for a broad range of topic areas under its purview, including hydraulics, dredging, coastal engineering, instrumentation, oceanography, remote sensing, geotechnical engineering, earthquake engineering, soil effects, vehicle mobility, self-contained munitions, military engineering, geophysics, pavements, protective structures, aquatic plants, water quality, dredged material, treatment of hazardous waste, wetlands, physical/mechanical/ chemical properties of snow and other frozen precipitation, infrastructure and environmental issues for installations, computer science, telecommunications management, energy, facilities maintenance, materials and structures, engineering processes, environmental processes, land and heritage conservation, and ecological processes.

Read the ERDC BAA here

2025 Army Geospatial Center (AGC) Broad Agency Announcement

Department of Defense – Department of the Army

Solicitation #: W5J9CQ25R0002

Deadline: White Papers are accepted through 10/13/2026

Amount: Not specified

The U.S. AGC is a Major Subordinate Command (MSC) under the U.S. Army Corps of Engineers (USACE) located at the Humphreys Engineer Center in Alexandria, Virginia. The AGC focus is on the Army’s Geospatial Enterprise function from Policy to Warfighting; supporting the Army’s Mission Command Systems by facilitating collection, management, exploitation; and dissemination of relevant geospatial information and products to every level across the operational environment. This general announcement addresses a wide variety of geospatial topic areas of research for the Systems and Acquisition Support Directorate. These research areas are described in the full text of the BAA.

Read the AGC BAA here

Naval Air Warfare Center Weapons Division (NAWCWD) Broad Agency Announcement

Department of Defense – Department of the Navy

Solicitation #: N6893626R0006

Deadline: Open through 9/30/2026

Amount: Not specified

NAWCWD at China Lake, CA is interested in receiving proposals for Naval Air Warfare and Weapons which offer potential for advancement and improvement of Navy and Marine Corps operations. This announcement declares NAWCWD’s broad role in competitive funding of research across a spectrum of science and engineering disciplines. Areas of interest include:

  1. Aerospace science research focuses on weapons and aerospace technologies  which directly support naval science and technology requirements for joint  strike warfare involving air superiority and precision attack, and air and surface battle space requirements of joint littoral aircraft involving  aircraft, naval surface fire support and ship self-defense.
  2. Air warfare and naval weapons applications focus on applied research and advanced technology development aligned with current and future naval capability gaps and innovative naval prototypes

Read the NAWCWD BAA here

Biological Technologies Office BAA

Department of Defense – DARPA

Solicitation #: HR001126S0003

Deadline: Open through 9/30/2026

Amount: Not specified

The Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO) is soliciting proposals that leverage biological properties and processes to revolutionize our ability to protect the nation’s warfighters. BTO harnesses advances in artificial intelligence (AI) and machine learning (ML) to create new opportunities for transformative science across the biological spectrum. Warfighter health and well-being are critical to mission success. BTO develops diagnostic and assessment systems to identify chemical and biological threats, medical countermeasures, and novel approaches to tactical care and warfighter performance and recovery on and off the battlefield. BTO also leverages biological processes, technologies, and manufacturing opportunities to create resilient infrastructures and supply chains, protective solutions, and innovative sensors to ensure mission success in any location.

Read the BTO BAA here

NRL: Long Range Broad Agency Announcement (BAA) for Basic and Applied Research

Department of Defense – Dept of the Navy

Solicitation #: N00173-24-S-BA01

Deadline: White papers accepted through 3/31/2026

Amount: Not specified

The Naval Research Laboratory (NRL) is interested in receiving innovative proposals that offer potential for advancement and improvement in a broad range of technical topic areas listed in the BAA. The purpose of this amendment is to extend the deadline for accepting white papers as well as update summary topics and email addresses of relevant contacts.

Read the BAA here

 

NeedipeDIA Broad Agency Announcement

Department of Defense – Defense Intelligence Agency

Solicitation #: HHM402-23-S-0001

Deadline: Submissions are accepted through 12/26/2028

Amount: Not specified

NeedipeDIA is a mechanism by which the Defense Intelligence Agency solicits and leverages ideas, practices, and capabilities created anywhere outside the organization that enhance the agency’s ability to fulfill its mission. Needs are derived throughout the year and are listed within the open BAA and the open CSO. Current broad areas of interest include: artificial intelligence and machine learning, enhancing counterintelligence and security, intelligence collections, mission enhancing science and technology, improving mission support capabilities, increasing organizational effectiveness, empowering partnerships, machine-assisted analytic rapid-repository systems, quantum information sciences, and emerging technologies.

Learn more and access the BAA here

Environmental Security Technology Certification Program (ESTCP) – Energy and Environmental Technology Demonstrations – Open Topics Broad Agency Announcement (BAA)

Department of Defense – Dept of the Army

Solicitation #: W912HQ25S0005

Deadline: White Papers are accepted through 8/21/2026

Amount: A total of $10M is available and multiple awards are anticipated

The Environmental Security Technology Certification Program (ESTCP) is the Department of Defense’s (DoD) demonstration and validation program for environmental and installation energy technologies. The ESTCP Office is interested in receiving white papers for innovative technology demonstrations that address DoD environmental and installation energy requirements as candidates for funding. ESTCP supports the demonstration and validation of technologies that:

  1. a) Increase energy security and grid independence through enhanced domestic energy production, microgrids, and advanced power generation
  2. b) Improve operational efficiency by reducing sustainment costs, enhancing logistics, and ensuring mission continuity
  3. c) Enhance installation resilience against extreme weather events, cyber threats, and physical disruptions
  4. d) Optimize defense infrastructure to ensure military bases, training grounds, and facilities remain fully functional and cost-efficient.

The program gives priority to technologies that strengthen the American industrial capacity, reduce reliance on foreign supply chains, and align with U.S. national security objectives. Technologies must be sufficiently mature for field demonstration, with proven feasibility and the potential for rapid transition into widespread DoD use.

Read ESTCP BAA

Strategic Environmental Research and Development Program (SERDP) – Open Topics Broad Agency Announcement (BAA)

Department of Defense – Dept of the Army

Solicitation #: W912HQ25S0004

Deadline: White Papers are accepted through 8/21/2026

Amount: A total of $10M is available and multiple awards are anticipated

The Department of Defense (DoD) Strategic Environmental Research and Development Program (SERDP) Office is interested in receiving white papers for research focusing in the areas of Environmental Restoration, Munitions Response, Resource Conservation and Resilience, and Weapons Systems and Platforms technologies. SERDP supports environmental research relevant to the management and mission of the DoD and supports efforts that lead to the development and application of innovative environmental technologies or methods that improve the environmental performance of DoD by improving outcomes, managing environmental risks, and/or reducing costs or time required to resolve environmental or resilience problems. The initial step is submission of a White Paper. Topic areas and research priorities within these topic areas include the following:

  • Environmental Restoration: Characterization and monitoring, reduction in cost to compete, reduce source loading of munitions constituents, stormwater treatment, wastewater treatment, and risk assessment.
  • Munitions Response: Wide area and/or detailed survey techniques, cost-effective recovery and disposal methods, and mobility of munitions in the dynamic underwater environment.
  • Resource Conservation and Resilience: Managing wildland fire, natural resources, and resilience of build and natural infrastructure.
  • Weapons Systems and Platforms: Manufacturing and maintenance; energetic materials and formulations; firefighting; and critical minerals, chemicals, and materials.

Read SERDP BAA

Research Interests of the Air Force Office of Scientific Research BAA

Department of Defense – AFRL Solicitation # FA955025S0001
Deadline: This announcement remains open until superseded
Amount: Awards typically range between $100K and $300K per year

This general Broad Agency Announcement outlines the U.S. Air Force Defense Research Sciences Program to solicit proposals for broad-based scientific and engineering research with the potential to profoundly impact future US Air Force and Space Force capabilities. Its focus is on research areas that offer significant and comprehensive benefits to our national warfighting and peacekeeping capabilities. These areas are organized and managed in two scientific branches, each with two teams:

  • Engineering and Information Sciences (teams include Engineering and Complex Systems and Information and Networks)
  • Physical and Biological Sciences (teams include Physical Sciences and Chemistry and Biological Sciences)

Please refer to the BAA for further details on the research areas managed within each team.

Read AFOSR BAA

Technologies for Forging BAA

Department of Defense – Defense Logistics Agency Solicitation # SP4701-25-B-0002
Deadline: White Papers and Proposals are accepted through 8/12/2030
Amount: Not specified
The purpose of this BAA stems from emerging and rapidly expanding requirements to (1) structure, execute, and coordinate projects that develop innovative solutions that can reduce the disproportionate number of DLA backorders, or unfilled orders for items that contain forgings, and (2) to improve the quality, productivity, technology, and business practices of the forging industry. The key focus areas are procurement solutions and manufacturing technologies.
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Artificial Intelligence and Next Generation Distributed Command and Control BAA

Department of Defense – AFRL Solicitation # FA875023S7006
Deadline: White Papers are accepted through 8/30/2028
Amount: Individual awards will range from $200K to $20M
Artificial Intelligence (AI) holds great potential in transforming the Department of the Air Force (DAF) and Joint Force Command and Control (C2) capabilities across strategic, operational, and tactical levels by enabling decision makers to effectively assess the battlespace, rapidly explore, create, and select the best plan, and direct and monitor forces at pace and scale in a distributed setting. This BAA is interested in exploring new and advancing existing AI and distributed C2 concepts. By accelerating the research & development of novel AI-based and distributed capabilities to support Joint All Domain C2, the DAF can achieve a strategic decision advantage, where AI becomes a key and prevalent component to future C2 systems. With the rise of AI-based applications also comes new challenges to include the ability to effectively manage, monitor, and adapt deployed AI capabilities and effective C2 in a distributed and contested environment. 
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Long Range BAA for the Undersea Security Program

Department of Defense – Dept of the Navy Solicitation # N00030-25-S-7002
Deadline: White Papers and Proposals are accepted through 8/10/2026
Amount: Not specified

The Department of the Navy’s Strategic Systems Programs (SSP) is interested in receiving proposals for the Long-Range S&T Projects that offer potential in support of the Undersea Security Program. There are two broad focus areas:

Focus Area #1: A Navy objective for this BAA is to focus on research and development services involving studies, analysis and assessments addressing a broad variety of areas such as Tactical Submarine Evolution Plan and Integrated Undersea Future Investment Strategy.

Focus Area #2: A Navy objective for this BAA is to focus on technology ideas that can impact the survivability of submarines and unmanned undersea systems.

See BAA for further details on projects sought under each Focus Area.

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Boosting Innovative GEOINT – Science & Technology Broad Agency Announcement

Department of Defense – National Geospatial-Intelligence Agency (NGA) Solicitation # HM0476-23-BAA-0001
Deadlines:

The BAA is open through 12/14/2026

Individual Topic Areas will have specific deadlines

Amount: Not specified

The Boosting Innovative GEOINT-Science and Technology (BIG-ST) Broad Agency Announcement (BAA) invites proposers to submit innovative concepts to address hard GEOINT problems that align to one or more of the following technical domains: Foundational GEOINT, Advanced Phenomenologies, and Analytic Technologies.

The BIG-ST BAA is a general announcement of NGA’s research interest. The requests for abstracts and/or proposals are transmitted via Topic Calls that are published separately under the BIG-ST BAA General Solicitation at various times during the open period of the General Solicitation. 

The current active topic is Topic 5 – Better Ingested GEOINT – Identifying Artificial Intelligence and Manually Manipulated Media (BIGISLAND). Interested parties must have an account to log into the Classified IC-ARC to see the notice, and all associated RFP documents.

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BAA for Advancement of Technologies for Use by Special Operations Forces

Department of Defense US Special Operations Command Solicitation #

USSOCOM-BAAST-2020

 

Deadline: Quad Charts and White Papers are accepted through 12/31/2030
Amount: Not specified
USSOCOM is interested in receiving Quad Charts and White Papers from all responsible sources (reference FAR 9.1) from industry, academia, individuals, Federally Funded Research and Development Centers, National Laboratories, and Government laboratories capable of pursuing, developing, and evolving disruptive capabilities that must be made available to the SOF Operator within the next five to seven years to achieve mission success in the FOE. USSOCOM employs capabilities in all domains: terrestrial, maritime, air, space, human and cyber. SOF personnel place a premium on technologies that are small, lightweight, rugged, modular, multiuse, easy to use, have low power consumption, require minimum maintenance, open architectures, and designed for operation in extreme environments at the edge of operations. Technology designs should consider comprehensive signature management approaches enabling low visibility and clandestine capabilities.
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Naval Research Laboratory Long Range Broad Agency Announcement (BAA) for Basic and Applied Research

Department of Defense – Naval Research Laboratory Solicitation # N00173-24-S-BA01
Deadline: White papers may be submitted at any time
Amount: Not specified
The Naval Research Laboratory (NRL) requests white papers for long-range Science and Technology projects which may offer advancement and improvement potential for Navy and Marine Corps operations. The research conducted at NRL is a broadly based multidisciplinary program of scientific research and advanced technological development directed toward maritime applications of new and improved materials, techniques, equipment, systems and ocean, atmospheric, and space sciences and related technologies. Specific topics included in this BAA announcement may be accessed at https://www.nrl.navy.mil/Doing-Business/Contracts/Broad-Agency-Announcements/.
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Defense Sciences Office (DSO) Office-wide BAA

Department of Defense – DARPA Solicitation # HR001125S0013
Deadline: Executive Summaries, Proposal Abstracts, and Proposals are accepted on a rolling basis until 6/2/2026
Amount: Not specified

The Defense Advanced Research Projects Agency (DARPA) Defense Sciences Office (DSO) is soliciting proposals that investigate innovative approaches that enable revolutionary advances in science, devices, or systems for national security applications. The DARPA DSO regularly publishes Broad Agency Announcements (BAAs) requesting responses to specific program topics. This announcement seeks revolutionary research ideas for topics not being addressed by ongoing DSO programs or other published solicitations. High-interest thrust areas include: Materials, Manufacturing, and Structures; Sensing, Measuring, and Affecting; Math, Computation, and Processing; and Complex, Dynamic, and Intelligent Systems.

To avoid proposals that duplicate existing activities or are responsive to other published DSO solicitations, potential proposers are highly encouraged to review current DSO programs and solicitations, respectively listed at http://www.darpa.mil/about-us/offices/dso and http://www.darpa.mil/work-with-us/opportunities. Contacting DSO program managers to discuss their research interests is strongly encouraged. A current list of program managers is available at http://www.darpa.mil/about-us/people.

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DEVCOM Army Research Laboratory Broad Agency Announcement for Foundational Research

Department of Defense – Dept of the Army Solicitation # W911NF-23-S-001
Deadline: Proposals are accepted on a rolling basis. BAA closes on 11/20/2027.
Amount: Not specified
The purpose of this BAA is to solicit research proposals for submission to the U.S. Army Combat Capabilities Development Command (DEVCOM) Army Research Laboratory (ARL) for funding consideration. ARL’s mission as the Army’s foundational research laboratory is to Operationalize Science to ensure overmatch in any future conflict. ARL’s foundational research mission spans basic research and applied research but may include advanced technology development and advanced component development and prototypes when opportunities arise to directly or indirectly help achieve ARL’s mission. ARL partners across the national security enterprise to deliver fundamentally advantageous change that is rooted in the creation and exploitation of scientific knowledge. See BAA for full list of topics.
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US Army Combat Capabilities Development Command BAA

Department of Defense – Dept of the Army Solicitation # W911QY25R0023
Deadline: White papers are accepted through 2/28/2030
Amount: Not specified

The Soldier Center is seeking solutions in the following scientific and technical areas:

  • Combat Feeding & Equipment – Ration development, field feeding systems
  • Soldier Protection & Survivability – Headborne protection, modular armor, chemical/biological protection, nanotechnology
  • Modeling & Simulation – Soldier effectiveness, operational survivability
  • Human Performance & Biomechanics – Body-worn systems, hand-held devices, soldier-centric sensors
  • Expeditionary Maneuver Support – Energy efficiency, EMI/EMP protection, battlefield mobility
  • Aerial Delivery – Advanced airdrop systems for personnel and cargo
  • Simulation & Training Technology – Medical training, AI-based battlefield visualization, cyberspace warfare training

This Broad Agency Announcement (BAA) is intended to fulfill requirements for scientific study and experimentation directed toward advancing state-of-the-art technologies and/or increasing knowledge and understanding as a means of eliminating current technology barriers. This BAA DOES NOT focus on specific systems or hardware solutions.

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AFRL Rocket Lab Hermes BAA

Department of Defense – AFRL Solicitation # FA9300-20-S-0001
Deadline: White papers are accepted on a rolling basis
Amount: Amounts for individual awards are not specified

The Air Force Research Laboratory (AFRL) is issuing an open Broad Agency Announcement (BAA) to solicit innovative research white papers related to rocket propulsion technologies. ​ This BAA aims to support the development of advanced missile and space vehicle propulsion systems over a 20-year open period. Specific technology areas for research include solid rocket motors, liquid rocket engines, and air-breathing turbine engines. ​Each area has defined topics for development, emphasizing advanced components, modeling tools, and rapid launch capabilities. ​

  • Solid Rocket Motor Technology Development: Focus on advanced components and manufacturing processes. ​
  • Liquid Rocket Engine Technology Development: Emphasis on disruptive engine concepts and modular systems. ​
  • Air-Breathing Turbine Engine Technology Development: Aims to enhance military propulsion capabilities. 
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FY25 Naval Air Warfare Center Aircraft Division Office-Wide Broad Agency Announcement

Department of Defense – NAVAIR Solicitation # N00421-25-S-0001
Deadline: White papers may be submitted any time through 6/22/2026
Amount: Not specified
The Naval Air Warfare Center Aircraft Division (NAWCAD) is interested in receiving white papers for research and development projects, which offer potential for advancement and improvement of NAWCAD operations. NAWCAD plays a broad role in competitive funding of meritorious research across a spectrum of science and engineering disciplines and has identified key research opportunity areas of interest needed to address the challenges, problems, and future technology needs of the Warfighter. The full list of research areas can be found in the NOFO, and areas considered the highest priority include Advanced Manufacturing, Artificial Intelligence/Machine Learning, Autonomy, Cyber, Digital Engineering, Quantum, and Secure Communications & Networks.
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Broad Agency Announcement (BAA) C4ISR, Information Operations, Cyberspace Operations and Infomation Technology System Research, Cryogenics and Quantum

Department of Defense – Naval Information Warfare Center Pacific Solicitation # N660013-25-S-BAA01
Deadline: White papers may be submitted at any time
Amount: Not specified
The Naval Information Warfare Center (NIWC) Pacific invites white papers and proposals for research projects aimed at advancing Command, Control, Communications, Computers, Intelligence, Surveillance, and Reconnaissance (C4ISR) capabilities. This BAA also supports enabling technologies for Information Operations, Cyberspace Operations, and related Information Technology systems. Funding may be awarded as contracts, grants, cooperative agreements, or other transaction agreements. NIWC Pacific seeks innovative approaches to developing next-generation, integratable C4ISR and command suite technologies. Proposals must align with full and open competition standards per the Competition in Contracting Act.
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Air Force Defense Research Sciences Program BAA

Department of Defense – AFOSR Solicitation # FA955025S0001
Deadline: This announcement will remain open until it is superseded
Amount: Research proposals typically are funded between $100K and $300K per year. Most awards are 3 years in duration.
Through this BAA, the AFOSR solicits proposals for broad-based basic research with the potential to profoundly impact future US Air Force and Space Force capabilities. The focus is on research areas that offer significant and comprehensive benefits to our national warfighting and peacekeeping capabilities. These areas are organized and managed in two scientific branches: Engineering and Information Sciences and Physical and Biological Sciences. See the BAA for a comprehensive description of the research areas within these branches.
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Broad Agency Announcement for Battery Network (BATTNET)

Department of Defense – Defense Logistics Agency Solicitation # BAA006-21
Deadline: Open through 9/1/2026
Amount: Not specified
As a Combat Support Agency, DLA’s mission is to provide logistics support to the warfighter. DLA’s BATTNET Manufacturing Technology R&D Program is intended to advance this essential service to our warfighters around the globe. The objective of the Program is to improve Department of Defense (DoD) battery logistics by leveraging advanced manufacturing technologies for the U.S. industrial base.  DLA seeks to provide responsive, best value supplies in a manner that consistently meets customer needs. DLA continually investigates diverse technologies for manufacturing that would lead to the highest level of innovation in battery products supporting fielded weapon systems (many of which were designed in the 1960’s, 1970’s, and 1980’s) with a future impact on both commercial technology and government applications. The types of research and development that are of interest in this BAA include advanced technology demonstrations for affordability, advanced industrial practices to demonstrate the combination of improved battery manufacturing and operation, unit cost reduction, and improved battery product availability. All these areas provide potential avenues toward achieving breakthrough advances.
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Broad Agency Announcement for Fundamental AI Research

Department of Defense – Dept of the Army Solicitation # W519TC-25-S-0001
Deadline: Open through 5/31/2029
Amount: Not specified
The Army Artificial Intelligence Integration Center (AI2C) is seeking artificial intelligence research and development whitepapers and proposals in support of new technologies and translational research-based approaches that support the identification, alignment, and exploitation of basic, applied, and advanced research. A broad range of foundational research topics of interest are described in the solicitation.
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Air Dominance Broad Agency Announcement

Department of Defense – Air Force Research Laboratory Solicitation # FA865125S0001
Deadline: White papers accepted through 10/31/2029
Amount: Not specified
This BAA is intended to support research relevant to the Munitions Directorate divisions of the Air Force Research Laboratory, including the Technology Integration Division, the Strategy Division, and the Science and Technology Division. The range of research areas covered by this BAA are described in the solicitation.
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Academic Applied and Advanced Innovation Broad Agency Announcement

Department of Defense – ARL Solicitation # ARL-BAA-0107
Deadline: Proposals accepted until 11/19/2027
Amount: Not specified

This program focuses on emerging and novel research conducted through academic institutions such as universities and academic-affiliated research institutions or centers. It covers broad technical areas of applied (6.2) and advanced technology development (6.3) research investigations that result in deliverables such as hardware, software, or knowledge products that support technology readiness levels (TRL) 3, 4, 5, and 6 and enable significant improvements in capability or system performance. Preferred research focuses on increasing capabilities, efficiencies, logistics and support; discovering new applications; conducting experiments; informing future requirements; and accelerating delivery of technology for Army transformation. Desired research completes within 12-24 months and extends by exception.

Thrust areas include but are not limited to the following:

·                Weapon systems and lethality technologies

·                Ground vehicle technologies

·                Networking and communications technologies

·                Sensing technologies

·                Air platform and aviation technologies

·                Soldier performance technologies

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United States Military Academy Broad Agency Announcement

DoD – Dept of the Army Solicitation # W911NF-20-S-0008
Deadline: Open through 3/31/2027
Amount: Not specified
The U.S. Military Academy at West Point executes research to enhance the education of cadets, develop the faculty professionally, and address important issues facing the Army and the Nation. In addition, the Academy conducts research and analysis in emerging fields that may realize novel or vastly improved Army capabilities. USMA departments, directorates, and research centers and institutes conduct research in-house and fund extramural research as solicited through this BAA. This BAA seeks proposals for research based on the following campaigns: Socio-Cultural; Information Technology; Ballistics, Weapons, and Protections; Energy and Sustainability; Materials, Measurements, and Facilities; Unmanned Systems and Space; Human Support Systems; and Artificial Intelligence, Machine Learning, and Quantum Technologies. Proposals are sought for cutting-edge innovative research that could produce discoveries with a significant impact to enable new and improved Army technologies and related operational capabilities and related technologies. 

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Targeting Operations and Analytics Development Broad Agency Announcement

DoD – Dept of the Air Force Solicitation # FA875025S7002
Deadline: Open through 9/30/2029
Amount: Average range of individual awards is $1M – $25M over 3 years
The Air Force Research Laboratory is soliciting white papers under this Broad Agency Announcement (BAA) for research, development, integration, test and evaluation of technologies/techniques to improve the joint targeting cycle by shortening the killchain, improving the speed of decisions, providing information and connectivity assurance during execution, and enabling battle damage assessment. These technologies should address one or more of the following focus areas: Dynamic Targeting and Engagement at Scale, Mission Communications, Combat Assessment, Indications & Warning Analytics, and Test & Evaluation.
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U.S. Army Combat Capabilities Development Command Soldier Center – Broad Agency Announcement (BAA) for Basic and Applied Research

DoD – Dept of the Army Solicitation # W911QY-20-R-0022
Deadline: Open through 2/27/2030
Amount: Not specified
The mission of the U.S. Army Combat Capabilities Development Command Soldier Center (DEVCOM Soldier Center) is to “provide the Army with innovative science and technology solutions to optimize the performance of our Soldiers”. To achieve the advances required for the Army to operate, organize, and equip in response to evolving threats, the Soldier Center is interested in efforts in five research focus areas: emergent materials; human performance and training; machine learning/artificial intelligence; robotics and autonomy; and synthetic biology. This BAA is intended to fulfill requirements for scientific study and experimentation directed toward advancing state-of-the-art technologies and/or increasing knowledge and understanding as a means of eliminating current technology barriers.
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Naval Undersea Warfare Center Division Science and Technology Broad Agency Announcement (BAA)

DoD – Dept of the Navy Solicitation # N66604-25-R-0329
Deadline: Open through 3/18/2030
Amount: Not specified
The Naval Undersea Warfare Center Division, Newport, (NUWCDIVNPT) is soliciting research proposals for new and innovative R&D solutions related to 27 undersea technology subject areas listed in the BAA.
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Multi-Spectrum Defensive Electronic Warfare (MSDEW) Advanced Research Announcement (ARA)

Department of Defense – Air Force Research Laboratory Solicitation # FA8650-20-S-1119
Deadlines: Open through 7/13/2027
Amount: Not specified
MSDEW ARA will develop sensors and systems supplies to meet the need for the national defense for improved joint lethality in contested environments, the ability to strike diverse targets inside adversary air and missile defense networks, and support a force which can deploy, survive, operate, maneuver, and regenerate in all domains while under attack. The program advances the Air Force EW (signal) capabilities to meet the need for the national defense and requires acquisition of aeronautical supplies, parts, accessories and designs for experimental and test purposes. These above strategic objectives will be accomplished through design, modeling, simulation and analysis (MS&A), experimentation, testing, and demonstration of multi-spectrum threat warning and countermeasures sensors, systems and technologies. 
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FY25-29 Strategic Trends Research Initiative Broad Agency Announcement

This is a Broad Agency Announcement (BAA) soliciting strategic research on challenges related to weapons of mass destruction (WMD) 5–10 years in the future in support of the mission of the Defense Threat Reduction Agency (DTRA). The BAA covers Fiscal Year (FY) 2025–2029 with a total funding amount of $35,880,000, subject to availability of funds. This BAA will remain posted on the Government point of entry, https://sam.gov/content/home until superseded.

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BAA for Chemical Biological Radiological Nuclear and Explosive (CBRNE) Defense Efforts

Department of Defense – Dept of the Army Solicitation # W911SR-24-R-DEVB
Deadline: Open until 8/20/2029
Amount:  
The U.S. Army Combat Capabilities Development Command Chemical Biological Center (DEVCOM CBC) mission is to provide innovative chemical, biological, radiological, nuclear and explosive (CBRNE) defense capabilities to enable the Joint Warfighters’ dominance on the battlefield and interagency defense of the homeland. Mission areas and technical points of contact for within DEVCOM CBC are shown in the Broad Agency Announcement. Proposals are sought from all eligible sources as specified herein, including educational institutions, nonprofit organizations, and private industry. This BAA provides general information, proposal preparation instructions, evaluation and selection criteria, and award administration.
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BAA Disruptive Application – Army Application Lab

Army Application Lab Solicitation # W911NF-24-S-0008
Deadline: Apr 04, 2029

The three main lines of effort associated with this BAA are discovery, acceleration, and translation of disruptive technology applications:

Discovery of novel capability concepts that capitalize on emerging technologies and application insights from the widest possible range of sources.

Acceleration of disruptive applications of technology that delivers a 2-4 times improvement over current or planned Army capabilities through the research, development, and validation of technology demonstrators.

Translation of breakthrough innovations that create a scalable, first-mover advantage for the Army in strategic technology areas by synchronizing knowledge generated in the discovery and acceleration phases with key decision points across the Army Future Force Modernization Enterprise (FFME).

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Computational Modeling of Aviation Systems BAA

Department of Defense – Army Research Laboratory Solicitation # ARL-BAA-0101
Deadline: Proposals are accepted through 11/19/2027
Amount: Not specified
Next-generation Army aviation platforms will need to integrate novel technologies in multiple areas including aerodynamics, acoustics, structural dynamics, and flight controls. These technologies will be evaluated in computational and experimental environments for real-world applications. Fundamental modeling and analysis capabilities also need to be developed at different degrees of fidelity from low fidelity for conceptual design and trade-space exploration to high fidelity for detailed design or scientific exploration. Novel technologies for next-generation Army aviation platforms are sought, including both manned platforms and unmanned aerial systems (UAS). Associated modeling and simulation approaches for these technologies will be required at varying degrees of fidelity to accommodate assessments at different stages of design and analysis processes including conceptual, preliminary, and detailed design stages.
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Mechanical Metamaterials for Advanced Protection BAA

Department of Defense – Army Research Laboratory Solicitation # ARL-BAA-0096
Deadline: Proposals accepted through 11/19/2027
Amount: Not specified

DEVCOM ARL is seeking proposals on the exploration and maturation of mechanical metamaterials and associated concepts, testing/diagnostics methods for characterization, scale-up methods etc., in a manner relevant to ballistic impact conditions. Novel manufacturing and processing techniques are of interest, provided that the work will involve high strain rate relevant characterization. Research in this area seeks to understand and control/manipulate material behavior to ballistic advantage, understand behavior on various scales, advanced modeling and simulation associated with these materials for enhanced understanding and further design/development of mechanical metamaterials.

Specific research areas include:

  • Mechanical metamaterials, nanostructured composites, engineered materials specifically built for manipulating shock and damage propagation due to ballistic impact and penetration.
  • Special consideration for increasing thickness, towards building 3D mechanical metamaterials.
  • Fundamental systematic studies to link manufacturing/synthesis process, nano/microstructure, mechanical properties, high strain rate properties, and ballistic performance.
  • Use or development of machine learning based approaches to aid in material discovery and design of mechanical metamaterials when there is no ‘big data’.
  • Modeling and simulation of such structures at various scales.
  • Multi-scale modeling approaches, verification, and validation involving mechanical metamaterials.
  • Developing/using experimental techniques and diagnostics to assess/characterize mechanical metamaterials. Scaling effects associated with small scale experimentation of such materials, and exploration of how they translate to continuum scale dynamic properties and performance.
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Scientific Feasibility (SciFy)

The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative and revolutionary computational approaches that measure the feasibility of technical claims to enable accurate assessments of scientific content.

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NRL Long Range Broad Agency Announcement (BAA) for Basic and Applied Research

NRL requests white papers for long-range Science and Technology (S&T) projects which may offer advancement and improvement potential for Navy and Marine Corps operations. This announcement emphasizes NRL’s broad role in the competitive funding of meritorious research across a spectrum of science and engineering disciplines.

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DOD Strategic Capabilities Office Broad Agency Announcement

Strategic Capabilities Office (SCO) is an organization within the Office of the Secretary of Defense which seeks to identify, analyze, and prototype disruptive applications of new systems, unconventional uses of existing systems, and implement emerging technologies to create operational strategic effects. SCO is a rapid prototyping organization focused on delivering capabilities in 3-5 years to address high priority operational and strategic challenges.

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DARPA Defense Sciences Office Office-wide

This opportunity is to identify and create the next generation of scientific discovery to fuel innovation throughout the Agency and beyond. DSO frames its office according to the thrust areas described further below, but encourages any fundamental research concept, idea, or effort that addresses DARPA’s mission to make pivotal investments in breakthrough technologies for national security.

Novel Materials & Structures: This thrust includes, but is not limited to, science and technology in quantum devices, atomic scale systems, and functional and structural materials.

Sensing & Measurement: This thrust includes but is not limited to, science and technology in quantum sensing and metrology, seeing (sensing) the unseen, and novel light sources.
Computation & Processing: This thrust includes, but is not limited to, science and technology of quantum computing, cryptography, and modeling of complex systems.
Enabling Operations: This thrust includes, but is not limited to, technologies to support spacebased operations, tactically remote environments, and resource assurance.
Collective Intelligence: This thrust includes, but is not limited to, exploration of complex social systems, adaptable Artificial Intelligence (AI), and AI-accelerated learning.
Emerging Threats: This thrust includes, but is not limited to, national security concerns related to global issues associated with raw material availability, environmental catastrophes, and digital societies.

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U.S. Air Force Research Laboratory (AFRL) Broad Agency Announcement on Enabling Cyber-Linked Physical Sensing Exploitation Accepting White Papers

This Broad Agency Announcement (FA8650-21-S-1016) on Enabling Cyber-Linked Physical Sensing Exploitation (ECLPSE) will be a Two Step, Open BAA to support research and analysis on cyber-physical sensing and Electronic Warfare (EW)-kinetic effects to enable understanding how cyber-connected devices interact with the physical environment found in manufacturing automation, utilities, transportation, agricultural, medical, and other common applications. This effort will also support research and analysis regarding the prevention and exploitation of information leakages similar to electromagnetic security (EMSEC) vulnerabilities in the cyber/EW-physical domain. Individual contracts will be up to $20M. The first step is submission of a white paper. Approved white paper offerors will receive Requests for Proposals. This BAA closes on February 25, 2026.

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DEVCOM Army Research Laboratory Broad Agency Announcement for Foundational Research – Updated Topic List

Department of Defense – Department of the Army Solicitation # W911NF-23-S-0001
Deadline: Proposals accepted through 11/20/2027
Amount: Not specified
This BAA solicits white papers and proposals for both basic and applied research across areas of interest to the ARL. The extensive list of topics has been updated and republished.
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Advanced Manufacturing Research in support of the Sciences of Extreme Materials Competency – Closing date Nov. 19, 2027

Army modernization requires a set of robust manufacturing strategies and integrated capabilities that enable a highly connected and collaborative enterprise. Agile manufacturing involves digitally enabled advanced manufacturing (AdvM) technologies with ubiquitous access to rapid prototyping, small-scale production, materials by design, etc. that are capable of scalable, and on-demand distributed production of components and systems. Agile manufacturing integrates the procedures, resources, and preparation that are needed to respond to changes in the demand utilizing systems, resources, and practice to react to these demands and adapt quickly without jeopardizing the Army’s ability to meet the performance requirements.

This area seeks transformational materials that can operate in extreme conditions, and methods to manufacture them readily in the organic US industrial base as well as in austere environments at the point of need. Next generation Army components and systems will need to integrate novel structures of unmatched geometric complexity, and novel materials produced using novel data driven digital manufacturing methods. Topics of interest include:  Additive manufacturing, Artificial intelligence (AI) and machine learning (ML) techniques for AdvM, Printed hybrid electronics including multi-functional devices and structures, Novel and robust design methodologies for convergent manufacturing, and more. 

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Electric- and Magnetic-Field Sensor Technology – Closing date Nov. 19, 2027

Research proposals are desired that are related to small, rugged, low-power electric- and magnetic-field sensors that can be deployed on a battlefield using artillery-based delivery systems, or scattered from air or ground vehicles, or emplaced by individual soldiers. These sensors should be passive or semi-active (i.e., with no local field-generating element), and may operate at low frequencies in the quasi-static zone (or “near field”), where the electric and magnetic fields are not coupled. These sensors should be characterized by exceptionally low power, size, weight, and cost, and/or by exceptionally high sensitivity and low noise (i.e., with performance limited by the background environment). Sensor bandwidth generally falls between DC and ~1 MHz, but may be further limited for specific applications: e.g., 0.001-10 Hz for anomaly detection; 30-3000 Hz for electric-power sensing; 3-30 kHz for very low frequency (VLF) sensing.

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Invincible Materials Research in support of the Sciences of Extreme Materials Competency – Closing date Nov. 19, 2027

The invincible materials portfolio focuses on the fundamental, basic and applied material science and engineering to identify novel and emerging materials, systems and technologies for use across multiple high valued platforms and systems. The portfolio seeks to expand knowledge of materials and the related science and engineering of all materials classes with respect to synthesis, processing, development of novel materials or feedstocks, methods, advanced manufacturing techniques, experimentation, high through put techniques, machine learning, characterization, and modeling and simulation. The portfolio seeks to enable the discovery, development, design and integration of emerging structural, chemical and biological protection, electronic, laser and energy, materials in traditional and extreme environments such as materials under high rate and dynamic conditions. The portfolio also seeks material science and manufacturing technologies that supports the soldier, combat vehicles, combat support vehicles and other high valued assets to enable improved performance and survivability.

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Invisible Materials Research in support of the Sciences of Extreme Materials Competency – Closing date Nov. 19, 2027

The Invisible Materials Portfolio seeks to identify novel electromagnetic spectrum materials (EMS) for use in a wide range of military applications. The portfolio seeks materials with advanced capabilities to increase, decreases or alter the energy emitted, scattered or absorbed in a controlled manner.

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Multimodal Synthetic Data for Machine Learning – Closing date Nov. 19, 2027

The use of artificial intelligence solutions for Army field applications will rely heavily on machine learning (ML) algorithms. Current ML algorithms need large amounts of mission-relevant training data to enable them to perform well in tasks such as object and activity recognition, and high-level decision making. Battlefield data sources can be heterogeneous, encompassing multiple sensing modalities. Present open-source data sets for training ML approaches provide inadequate representation of scenes and situations of interest to the Army, in both content and sensing modalities. There is a push to use synthetic data to make up for the paucity of real-world training data relevant to military multi-domain operations of the future. However, there are no systematic approaches for synthetic generation of data that provide any degree of assurance of improved real-world performance of the ML techniques trained on such data. The problem of effective synthetic data generation for ML raises deeper questions than that of artificially generating speech or imagery that humans find realistic.

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DOD Tactical Heterogeneous Sensing in Complex Environments, Aerosols, and Impacts- November 19, 2027

 This program focuses on basic and applied research investigations designed to enhance situational and operational awareness with respect to operations in complex, multi-domain environments enabling C4ISR and maneuver capabilities. The research covers a broad portfolio including aerosol sciences, propagation of electro-optic (EO), electro-magnetic (EM), radio-frequency (RF) and acoustic signals in complex environments, impacts thereof, and heterogeneous sensing. Areas of specific interest are optical spectroscopy and characterization of aerosols, modeling of light interaction with material, atmospheric aerosol composition, heterogeneous remote sensing, and propagation modeling. Complex environments of particular interest are urban, littoral, forested, and domain interfaces.

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DOD Quantum networking for communications, distributed entanglement and information processing – November 19, 2027

 The Army seeks proposals in the development of quantum networks to advance performance metrics across a range of applications, including information distribution/security/processing, logistics, conventional networking and computing.

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DARPA – Microsystems Technology Office: Intensity-Squeezed Photonic Integration for Revolutionary Detectors (INSPIRED) 

DARPA’s Microsystems Technology Office seeks innovative proposals to develop compact, ultralow-noise optical detectors that employ squeezed-light measurement techniques to advance precision optical sensing. Specifically excluded is research that primarily results in evolutionary improvements to the existing state of practice.

The principal objective of the Intensity-Squeezed Photonic Integration for Revolutionary Detectors (INSPIRED) program is the development of optoelectronic detector modules that integrate squeezed-light measurement techniques into form factors comparable to commercial photodetector modules, thereby achieving sensitivity significantly beyond the quantum shot-noise limit. Such “squeezed-light detectors” will be transformative in advancing squeezed-light quantum measurement beyond laboratory environments as practical, general-purpose detector components that can be employed in diverse optical systems. The superior sensitivity of squeezed-light detectors is expected to provide decisive quantum advantages in wide-ranging application domains such as active imaging; atomic sensing; navigation; microscopy; and communications.

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NIST

CHIPS Research and Development Office (CRDO) Broad Agency Announcement

Department of Commerce – NIST

Solicitation #: 2025-NIST-CHIPS-CRDO-01

Deadline: Applications are accepted on a rolling basis through 9/30/2029

Amount: Project budgets should be at least $10M for up to 5 years

NIST is soliciting proposals from eligible applicants for research, prototyping, and commercial solutions that advance microelectronics technology. Proposals will grow U.S. leadership in semiconductor technology and accelerate the pace of commercialization in the industries of the future, in areas including advanced microelectronics research and development with a nexus to Artificial Intelligence (AI), Quantum Technology, Biotechnology, Biomanufacturing, Commercialization of Innovation, and/or Standards Development.

CRDO will host an informational webinar to provide general information regarding this BAA, offer general guidance on preparing White Papers and if invited, Pre-negotiation Packages, and answer questions submitted in advance. The date for the webinar has not yet been announced; RTT will share this date once it is announced. Interested parties may also sign up for the CHIPS mailing list to ensure they receive future communications about this opportunity.

Read the BAA here

Measurement Science and Engineering (MSE) Research Grant Programs

Department of Commerce – NIST Solicitation # 2024-NIST-MSE-01
Deadline: Proposals accepted on a rolling basis through 3/5/2026
Amount: Varies by program

This broad NOFO seeks to fund education and research activities across the following NIST programs:

(1)   Associate Director for Innovation and Industry Services (ADIIS);

(2)   Associate Director for Laboratory Programs (ADLP);

(3)   CHIPS Research & Development Program Office (CRDO)

(4)   Communications Technology Laboratory (CTL);

(5)   Engineering Laboratory (EL);

(6)   Fire Research (FR);

(7)   Information Technology Laboratory (ITL);

(8)   International and Academic Affairs Office (IAAO);

(9)   Material Measurement Laboratory (MML);

(10) NIST Center for Neutron Research (NCNR); 

(11) Physical Measurement Laboratory (PML);

(12) Special Programs Office (SPO); and

(13) Standards Coordination Office (SCO).

Refer to the solicitation for specific activities and funding levels related to each program.

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NOAA

FY 2024-2026 Office of Oceanic and Atmospheric Research (OAR)

Department of Commerce – NOAA Solicitation # NOAA-OAR-CPO-2024-28363
Deadline: Open until 9/30/2026
Amount: Not specified
The NOAA Office of Oceanic and Atmospheric Research is responsible for maintaining and improving the viability of marine and coastal ecosystems; for delivering valuable weather, climate, and water information and services; for understanding the science and consequences of climate change; and for supporting the global commerce and transportation upon which we all depend. This Broad Agency Announcement is a mechanism to encourage research, education and outreach, innovative projects, or sponsorships that are not addressed through NOAA’s competitive discretionary programs.
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Information Innovation Office (I2O) Office-Wide Broad Agency Announcement

National Ocean Services (NOS) Line Office FY 2024-2026 BAA
NOAA Solicitation # NOAA-NOS-MB-27779
Deadline: Proposals accepted on a rolling basis through 9/30/2026
Oceanic and Atmospheric Research (OAR) Line Office S&T FY 2024-2026 BAA
NOAA Solicitation # NOAA-OAR-OER-2024-27749
Deadline: Proposals accepted on a rolling basis through 9/30/2026
FY 2024-2026 BAA for the Office of Education
NOAA Solicitation # NOAA-SEC-OED-2024-28060
Deadline: Proposals accepted on a rolling basis through 9/30/2026

 

SCO

Strategic Capabilities Office (SCO) Broad Agency Announcement (BAA)

Secretary of Defense – SCO Solicitation # HY0233-SCO-24-BAA-0001
Deadline: Open until 8/31/2029
Amount: Not specified
SCO is an organization within the Office of the Secretary of Defense which seeks to identify, analyze, and prototype disruptive applications of new systems, unconventional uses of existing systems, and implement emerging technologies to create operational strategic effects.  SCO is a rapid prototyping organization focused on delivering capabilities in 3-5 years to address high priority operational and strategic challenges. The purpose of this BAA is to solicit research submissions for funding consideration in the five areas of technical interest, including: autonomous systems; deep learning; cyber; cross-domain kill chains; and non-traditional defense technologies. The first step in applying is to submit a white paper.
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Let Us Help You Get the Recognition Your Work Deserves

If you are aware of an honorific award that you would like to be nominated for, reach out to Jenny Crawford at jennycrawford@mines.edu for assistance with the nomination process.

Kavli Prize

Deadlines: Nomination window closes 10/1/2025
Amount: $1 million for individuals or groups of up to 3 researchers
Every other year, The Kavli Prize invites the community to nominate scientists whose basic research has fundamentally transformed the fields of astrophysics, nanoscience and neuroscience – the big, the small, and the complex. The prize consists of $1 million awards in each of the three fields and is awarded directly to the Laureate(s). A nomination consists of 5 simple steps, requiring a CV of the nominee(s), a nomination letter describing the work and impact of the nominee(s), and optional references. Anyone can nominate, but self-nominations are not accepted. Contact Jenny Crawford at jennycrawford@mines.edu for assistance with your nomination package.
Read more about the prize and the nomination process

Five Upcoming Opportunities with the Emerging Technology Accelerator (ETA): Notice of Intent and Proposers Day

Office of the Director of National Intelligence — IARPA

Notice ID #: n/a

Date: Proposers Day is 1/7/2026

The Emerging Technology Accelerator effort seeks to create new Intelligence Community (IC) technology advantage by bridging the technical gap between emerging solutions and successful application in the IC through lean, agile programs scoped to deliver capabilities directly applicable to intelligence needs with rigorous assessment of relevant performance. IARPA has five new topic areas for industry engagement and is hosting this proposers’ day to communicate expectations for the new type of program, discuss the technical goals, and to answer questions about them. Register for the proposers day here.

  • IARPA – COSMIC will allow the Intelligence Community to integrate temporally relevant geospatial information and imagery to answer key questions.
  • IARPA – DECIPHER’s goal is to create capabilities to detect specialized language of interest to a user and generate probable definitions for unfamiliar, coded and novel terms.
  • IARPA – LocUS will improve the geolocation capabilities of the Intelligence Community (IC) considerably beyond imagery-only methods and thereby increase the volume of content that can be accurately geolocated.
  • IARPA – MOVES seeks create algorithms that aid clinicians in making diagnoses of a small set of neurological conditions using less than ideal or challenging video that may be taken from non-clinical angles and which may also include obstructed views and fully clothed subjects.
  • IARPA – ARCADE seeks to accelerate electrical circuit design within the Intelligence Community to enable faster response to emerging national security threats at an unprecedented level of speed, reliability, and innovation.

Future Program Announcement: I-MaDe

Department of Defense – DARPA

Solicitation #: DARPA-SN-26-10

Anticipated Release Date: Not specified

The Defense Advanced Research Projects Agency (DARPA) Microsystems Technology Office (MTO) is contemplating a new research area of interest in the Inorganic Materials on Demand (I-MaDe) program and is providing notice of a potential future call. I-MaDe aims to accelerate microsystem innovation by creating new tools and techniques to enable therapid development of new complex thin film inorganic materials at scale, ensuring the demands of future Department of War (DoW) systems are met.

Read the notice of intent here

Notice of Intent: High Performance Computing for Energy Innovation (HPC4EI) Initiative

Department of Energy – AMMTO/EERE

NOI #: HPC4EI25posting

Anticipated Release Date: Not specified

The HPC4EI program provides U.S. manufacturers access to Department of Energy National Laboratory expertise and cutting-edge supercomputing resources. These collaborations allow companies to tackle complex challenges in energy and materials, reduce costs, improve efficiency and performance, strengthen supply chain resilience, and expand U.S. industrial competitiveness in global markets. The solicitation will target qualified industry partners to participate in short-term, collaborative projects with DOE national laboratories. Eligibility for the program is limited to entities that manufacture products or conduct operations in the United States for commercial applications, as well as to organizations that support these entities. This focus ensures the equitable use and benefits of HPC national laboratory resources and technologies. Selected projects will be awarded up to $400,000 to support computing cycles and work performed by DOE national laboratories, universities, and non-profit partners.

Read HPC4EI Notice of Intent

Notice of Intent: Mission Atlas

Department of Energy – Office of Science

NOI #: n/a

Anticipated Release Date: November 2025

The DOE is preparing to launch Mission Atlas, a major initiative under its Frontiers in Artificial Intelligence for Science, Security and Technology (FASST) program, which was announced last summer. The effort is designed to accelerate the use of artificial intelligence across national laboratories, universities, and industry to “double scientific efficiency to increase GDP.” Mission Atlas will fund research partnerships that use AI to advance both basic and applied science. The goal is to develop large language models, sometimes described as a “physicsGPT” to enhance discovery and innovation.

Collaboration opportunities will be centered at DOE National Laboratories and involve partners from academia and industry. The formal announcement was expected this week but has been delayed to next week. Congressional staff were briefed only recently on the project’s scale and scope. The initiative seeks to demonstrate how advanced AI applications can improve the pace and impact of federally funded research, serving as a model for future science and technology programs. DOE anticipates initial funding of up to $750 million, with potential growth to $2 billion annually to support partnerships across sectors. A full-year continuing resolution (CR) could significantly impact implementation, but OSTP Director Kratsios has confirmed that the administration views this program as a model for structuring future federal research initiatives. More information will be shared as it becomes available.

Screening for Conditions by Electronic Nose Technology (SCENT III)

National Institutes of Health

Solicitation #: RFA-TR-26-001

Anticipated Release Date: 2/5/2026

This NOFO seeks to develop electronic nose technologies that mimic the olfactory system, leading to a robust diagnostic platform subject to validation and regulatory approval. A previous iteration demonstrated the feasibility of developing safe and effective biosensing technologies for volatile organic compound (VOC) signatures from human skin through systems engineering and artificial intelligence. VOCs are biomarkers that underlie the effects of a wide array of diseases. Under this iteration of the NOFO, improved sensing, detection, and analytical technologies will be developed for integration into tools for disease diagnosis and monitoring in everyday settings. These novel technologies will complement traditional blood analysis and other invasive, expensive, and highly technical procedures to monitor the onset, progression, and resolution of disease. The vision of the National Center for Advancing Translational Science (NCATS) is to bring more treatments for all people more quickly. The electronic nose platform is noninvasive and makes diagnosis in real time, in situ. This NOFO seeks to improve the translation of existing knowledge for the prevention and treatment of various diseases conditions.

Learn more about this forecasted funding opportunity here

Notice of Intent: Bioengineering Research, Innovation and Technology Education (BRITE) Program

National Institutes of Health

Solicitation #: PAR-26-025

Anticipated Release Date: 2/9/2026

The Bioengineering Research, Innovation and Technology Education (BRITE) Program is designed to foster the development of undergraduate freshmen and sophomores to pursue further studies and careers in bioengineering, biomedical imaging or other STEM fields relevant to NIBIB’s scientific mission. Applications are encouraged to propose integrated educational activities that include three elements: 1) a summer bridge program for incoming freshmen, and 2) in the freshman and sophomore years, educational activities during the academic year, and 3) summer research experiences. The BRITE program is intended to expose students to bioengineering and biomedical imaging and provide research, innovation and entrepreneurship training early in their college careers by incorporating didactic, experiential, mentoring and career development opportunities. Student participants will receive support for the first two years of their undergraduate training. To enhance capacity for rigorous bioengineering training, this program will support programs at baccalaureate degree granting institutions with modest levels of NIH research project grant funding.

Learn more about this forecasted funding opportunity here

Notice of Intent: Bioengineering Research Grants (BRG)

National Institutes of Health – National Cancer Institute (NCI)

Solicitation #: PAR-25-458

Anticipated Release Date: 9/30/2025

Amount: Not specified

The purpose of this NOFO is to encourage collaborations between the life and physical sciences that: 1) apply a multidisciplinary bioengineering approach to the solution of a biomedical problem; and 2) integrate, optimize, validate, translate or otherwise accelerate the adoption of promising tools, methods, and techniques for a specific research or clinical problem in basic, translational, or clinical science and practice. An application may propose design-directed, developmental, discovery-driven, or hypothesis-driven research and is appropriate for small teams applying an integrative approach to increase our understanding of and solve problems in biological, clinical, or translational science. The NOFO is anticipated to be released on 9/30/2025 and applications will be due 2/5/2026.

Learn more about this forecasted funding opportunity here

 

Notice of Intent: Mapping Machine Learning to Physics (ML2P)

Department of Defense – DARPA Solicitation # DARPA-SN-25-101
Anticipated Release Date: Not specified
Amount: Not specified
Machine learning (ML) moves fast, but it needs power. More power than we have, and that’s the problem. The Department of Defense faces additional constraints with ML deployments at the edge in resource-limited battlefield environments. The ML2P program is about prioritizing power efficiency consumption right from the start. ML2P will map ML efficiency directly to physics using precise Joule measurements, enabling accurate power and performance predictions across diverse hardware architectures. If a solicitation is issued, ML2P will develop multi-objective optimization functions that balance power consumption with performance metrics and discover how local optimizations interact through Energy Semantics of ML (ES-ML) to solve the energy-aware ML optimization problem.
Read Notice of Intent